Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome
Abstract Background We describe herein an extremely rare case of intracardiac ectopic thymoma—only two pure cases have been reported to date—associated with myasthenia gravis, an infrequent complication of ectopic thymoma. Case presentation A 71-year-old woman with superior vena cava syndrome was fo...
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| Format: | Article |
| Language: | English |
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Japan Surgical Society
2021-06-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-021-01233-4 |
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| author | Satoshi Takebayashi Yasuji Yoshikawa Masato Morita Ryotaro Nagashima Yuichi Nakazono Shinji Miyamoto |
| author_facet | Satoshi Takebayashi Yasuji Yoshikawa Masato Morita Ryotaro Nagashima Yuichi Nakazono Shinji Miyamoto |
| author_sort | Satoshi Takebayashi |
| collection | DOAJ |
| description | Abstract Background We describe herein an extremely rare case of intracardiac ectopic thymoma—only two pure cases have been reported to date—associated with myasthenia gravis, an infrequent complication of ectopic thymoma. Case presentation A 71-year-old woman with superior vena cava syndrome was found to have a large mass mainly located in the right atrium. Tumor resection under cardiopulmonary bypass was performed. The pathological diagnosis was type AB ectopic thymoma. The postoperative course was complicated by progressive respiratory failure, and she was diagnosed with myasthenic crisis based on clinical signs and the edrophonium test. The patient recovered and was weaned from prolonged mechanical ventilation after receiving intravenous immunoglobulin, and was subsequently discharged uneventfully. Conclusions This is the first report of myasthenic crisis due to intracardiac ectopic thymoma. Residual thymoma is a risk factor for the development of post-thymectomy myasthenia gravis, and long-term follow-up is required. |
| format | Article |
| id | doaj-art-706f74c0e2584e11b889e38d1c8f9976 |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-706f74c0e2584e11b889e38d1c8f99762025-08-20T03:33:54ZengJapan Surgical SocietySurgical Case Reports2198-77932021-06-01711510.1186/s40792-021-01233-4Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndromeSatoshi Takebayashi0Yasuji Yoshikawa1Masato Morita2Ryotaro Nagashima3Yuichi Nakazono4Shinji Miyamoto5The Department of Cardiovascular Surgery, National Hospital Organization Beppu Medical CenterThe Department of Pathology, National Hospital Organization Beppu Medical CenterThe Department of Cardiovascular Surgery, National Hospital Organization Beppu Medical CenterThe Department of Cardiovascular Surgery, National Hospital Organization Beppu Medical CenterThe Department of Pathology, National Hospital Organization Beppu Medical CenterThe Department of Cardiovascular Surgery, Oita University HospitalAbstract Background We describe herein an extremely rare case of intracardiac ectopic thymoma—only two pure cases have been reported to date—associated with myasthenia gravis, an infrequent complication of ectopic thymoma. Case presentation A 71-year-old woman with superior vena cava syndrome was found to have a large mass mainly located in the right atrium. Tumor resection under cardiopulmonary bypass was performed. The pathological diagnosis was type AB ectopic thymoma. The postoperative course was complicated by progressive respiratory failure, and she was diagnosed with myasthenic crisis based on clinical signs and the edrophonium test. The patient recovered and was weaned from prolonged mechanical ventilation after receiving intravenous immunoglobulin, and was subsequently discharged uneventfully. Conclusions This is the first report of myasthenic crisis due to intracardiac ectopic thymoma. Residual thymoma is a risk factor for the development of post-thymectomy myasthenia gravis, and long-term follow-up is required.https://doi.org/10.1186/s40792-021-01233-4Ectopic thymomaSuperior vena cava syndromeMyasthenia gravisMyasthenic crisis |
| spellingShingle | Satoshi Takebayashi Yasuji Yoshikawa Masato Morita Ryotaro Nagashima Yuichi Nakazono Shinji Miyamoto Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome Surgical Case Reports Ectopic thymoma Superior vena cava syndrome Myasthenia gravis Myasthenic crisis |
| title | Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome |
| title_full | Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome |
| title_fullStr | Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome |
| title_full_unstemmed | Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome |
| title_short | Myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome |
| title_sort | myasthenic crisis appearing after resection of intracardiac ectopic thymoma with superior vena cava syndrome |
| topic | Ectopic thymoma Superior vena cava syndrome Myasthenia gravis Myasthenic crisis |
| url | https://doi.org/10.1186/s40792-021-01233-4 |
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