Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets
Abstract Platelet-rich plasma (PRP) therapy has emerged as a potential treatment option for osteoarthritis (OA) due to its ability to promote tissue healing and anti-inflammatory effects. More evidences are needed to establish the optimal therapy protocol. We present here a retrospective analysis of...
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| Format: | Article |
| Language: | English |
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BMC
2025-04-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-025-08663-3 |
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| author | Adrien Schwitzguébel Alfredo Hernandez Corzo Efstathia Theodoridou Mitko Bogoev Matthieu Grange Sana Boudabbous Charles Benaim |
| author_facet | Adrien Schwitzguébel Alfredo Hernandez Corzo Efstathia Theodoridou Mitko Bogoev Matthieu Grange Sana Boudabbous Charles Benaim |
| author_sort | Adrien Schwitzguébel |
| collection | DOAJ |
| description | Abstract Platelet-rich plasma (PRP) therapy has emerged as a potential treatment option for osteoarthritis (OA) due to its ability to promote tissue healing and anti-inflammatory effects. More evidences are needed to establish the optimal therapy protocol. We present here a retrospective analysis of 252 patients treated with PRP for big joints OA between 2020 and 2022. We aimed to evaluate the benefits of PRP combined with rehabilitation on pain and function as well as the potential prognosis factors. We observed clinically significant improvements in pain (VAS improvement 49% at 6 months, 45% at 12 months) and function (Single Assessment Numeric Evaluation i.e. SANE score improvement 44% at 6 months, 39% at 12 months). Multiple PRP shoots and high sports activity, especially competition level, were found as favorable prognosis factors. The authors would suggest offering systematically PRP therapy for competition sports practitioners. Moreover, authors suggest that multiple PRP shoots, spaced from 3 to 4 weeks, could be a viable treatment option for OA. |
| format | Article |
| id | doaj-art-705f2efbe779428f8e94c468090b9bc6 |
| institution | OA Journals |
| issn | 1471-2474 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj-art-705f2efbe779428f8e94c468090b9bc62025-08-20T02:30:14ZengBMCBMC Musculoskeletal Disorders1471-24742025-04-0126111010.1186/s12891-025-08663-3Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of plateletsAdrien Schwitzguébel0Alfredo Hernandez Corzo1Efstathia Theodoridou2Mitko Bogoev3Matthieu Grange4Sana Boudabbous5Charles Benaim6Sports Medicine Department , Providence HospitalSports Medicine Department , Providence HospitalSports Medicine Department , Providence HospitalSports Medicine Department , Providence HospitalRadiology, Private PracticeRadiology Department, Geneva University HospitalRheumatology Department, Vaud University Hospital and University of LausanneAbstract Platelet-rich plasma (PRP) therapy has emerged as a potential treatment option for osteoarthritis (OA) due to its ability to promote tissue healing and anti-inflammatory effects. More evidences are needed to establish the optimal therapy protocol. We present here a retrospective analysis of 252 patients treated with PRP for big joints OA between 2020 and 2022. We aimed to evaluate the benefits of PRP combined with rehabilitation on pain and function as well as the potential prognosis factors. We observed clinically significant improvements in pain (VAS improvement 49% at 6 months, 45% at 12 months) and function (Single Assessment Numeric Evaluation i.e. SANE score improvement 44% at 6 months, 39% at 12 months). Multiple PRP shoots and high sports activity, especially competition level, were found as favorable prognosis factors. The authors would suggest offering systematically PRP therapy for competition sports practitioners. Moreover, authors suggest that multiple PRP shoots, spaced from 3 to 4 weeks, could be a viable treatment option for OA.https://doi.org/10.1186/s12891-025-08663-3OsteoarthritisChondropathyPlatelet-rich plasmaSports medicineJoint injections |
| spellingShingle | Adrien Schwitzguébel Alfredo Hernandez Corzo Efstathia Theodoridou Mitko Bogoev Matthieu Grange Sana Boudabbous Charles Benaim Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets BMC Musculoskeletal Disorders Osteoarthritis Chondropathy Platelet-rich plasma Sports medicine Joint injections |
| title | Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets |
| title_full | Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets |
| title_fullStr | Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets |
| title_full_unstemmed | Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets |
| title_short | Platelet-rich plasma treatment for large joint osteoarthritis: retrospective study highlighting a possible treatment protocol with long-lasting stimulation of the joint with an adequate dose of platelets |
| title_sort | platelet rich plasma treatment for large joint osteoarthritis retrospective study highlighting a possible treatment protocol with long lasting stimulation of the joint with an adequate dose of platelets |
| topic | Osteoarthritis Chondropathy Platelet-rich plasma Sports medicine Joint injections |
| url | https://doi.org/10.1186/s12891-025-08663-3 |
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