Intermediate-dose posttransplantation cyclophosphamide for myeloablative HLA-haploidentical bone marrow transplantation

Intermediate-dose posttransplantation cyclophosphamide for myeloablative HLA-haploidentical bone marrow transplantation

Abstract: High-dose posttransplantation cyclophosphamide (HD-PTCy), given at 50 mg/kg/day on days +3/+4, is a standard-of-care graft-versus-host disease (GVHD) prophylaxis for allogeneic hematopoietic cell transplantation (HCT). Our murine MHC–haploidentical HCT studies suggested intermediate-dose P...

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Main Authors: Mustafa A. Hyder, Dimana Dimitrova, Ruby Sabina, Ashley DeVries, Jeannine S. McCune, Meredith J. McAdams, Francis A. Flomerfelt, Christi McKeown, Jennifer L. Sadler, Amy Chai, Thomas E. Hughes, Scott Napier, Anita Stokes, Jennifer Sponaugle, Kamil Rechache, Mark Parta, Jennifer Cuellar-Rodriguez, William D. Figg, Hyoyoung Choo-Wosoba, Seth M. Steinberg, Jennifer A. Kanakry, Christopher G. Kanakry
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925000734
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