A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy

We treated a patient with neurosarcoidosis, which caused the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), in whom diagnosis was performed using neuroendoscopy. The patient was a 56-year-old female who was hospitalized for hyponatremia and diagnosed with SIADH based on a detai...

Full description

Saved in:
Bibliographic Details
Main Authors: Shiko Gen, Akio Ogawa, Koji Kanai, Kanako Nobe, Naofumi Ikeda, Atsuko Mochizuki, Kazuo Tokushige
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2018/9496149
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849413762351628288
author Shiko Gen
Akio Ogawa
Koji Kanai
Kanako Nobe
Naofumi Ikeda
Atsuko Mochizuki
Kazuo Tokushige
author_facet Shiko Gen
Akio Ogawa
Koji Kanai
Kanako Nobe
Naofumi Ikeda
Atsuko Mochizuki
Kazuo Tokushige
author_sort Shiko Gen
collection DOAJ
description We treated a patient with neurosarcoidosis, which caused the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), in whom diagnosis was performed using neuroendoscopy. The patient was a 56-year-old female who was hospitalized for hyponatremia and diagnosed with SIADH based on a detailed examination. During the course, she developed impaired consciousness due to acute hydrocephalus, which improved after ventricular drainage. Head magnetic resonance imaging (MRI) confirmed nodular lesions at the floor of the third ventricle and the cerebral aqueduct. Neuroendoscopic biopsy led to the diagnosis of neurosarcoidosis. Her hyponatremia improved after steroid therapy. Neurosarcoidosis can cause SIADH, and complication of hydrocephalus may lead to a poor prognosis. Neuroendoscopy appears to be effective for the diagnosis of neurosarcoidosis with hydrocephalus and helps in deciding the treatment modality.
format Article
id doaj-art-705498a15e544fd899eeec32c6e5cb4e
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-705498a15e544fd899eeec32c6e5cb4e2025-08-20T03:34:01ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/94961499496149A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with NeuroendoscopyShiko Gen0Akio Ogawa1Koji Kanai2Kanako Nobe3Naofumi Ikeda4Atsuko Mochizuki5Kazuo Tokushige6Department of Nephrology, Saitama Sekishinkai Hospital, Saitama, JapanDepartment of Nephrology, Saitama Sekishinkai Hospital, Saitama, JapanDepartment of Nephrology, Saitama Sekishinkai Hospital, Saitama, JapanDepartment of Nephrology, Saitama Sekishinkai Hospital, Saitama, JapanDepartment of Nephrology, Saitama Sekishinkai Hospital, Saitama, JapanDepartment of Neurology, Saitama Sekishinkai Hospital, Saitama, JapanDepartment of Neurosurgery, Saitama Sekishinkai Hospital, Saitama, JapanWe treated a patient with neurosarcoidosis, which caused the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), in whom diagnosis was performed using neuroendoscopy. The patient was a 56-year-old female who was hospitalized for hyponatremia and diagnosed with SIADH based on a detailed examination. During the course, she developed impaired consciousness due to acute hydrocephalus, which improved after ventricular drainage. Head magnetic resonance imaging (MRI) confirmed nodular lesions at the floor of the third ventricle and the cerebral aqueduct. Neuroendoscopic biopsy led to the diagnosis of neurosarcoidosis. Her hyponatremia improved after steroid therapy. Neurosarcoidosis can cause SIADH, and complication of hydrocephalus may lead to a poor prognosis. Neuroendoscopy appears to be effective for the diagnosis of neurosarcoidosis with hydrocephalus and helps in deciding the treatment modality.http://dx.doi.org/10.1155/2018/9496149
spellingShingle Shiko Gen
Akio Ogawa
Koji Kanai
Kanako Nobe
Naofumi Ikeda
Atsuko Mochizuki
Kazuo Tokushige
A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy
Case Reports in Medicine
title A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy
title_full A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy
title_fullStr A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy
title_full_unstemmed A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy
title_short A Case of Neurosarcoidosis-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone Diagnosed with Neuroendoscopy
title_sort case of neurosarcoidosis induced syndrome of inappropriate secretion of antidiuretic hormone diagnosed with neuroendoscopy
url http://dx.doi.org/10.1155/2018/9496149
work_keys_str_mv AT shikogen acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT akioogawa acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT kojikanai acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT kanakonobe acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT naofumiikeda acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT atsukomochizuki acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT kazuotokushige acaseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT shikogen caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT akioogawa caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT kojikanai caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT kanakonobe caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT naofumiikeda caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT atsukomochizuki caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy
AT kazuotokushige caseofneurosarcoidosisinducedsyndromeofinappropriatesecretionofantidiuretichormonediagnosedwithneuroendoscopy