Chronic starvation induces microglial cell depletion in an activity-based anorexia model

Chronic starvation induces microglial cell depletion in an activity-based anorexia model

Abstract Anorexia nervosa (AN) is a severe psychiatric disease with a largely unknown pathophysiology. AN leads to reduced brain volume and a disbalance of the gut microbiome suggesting the involvement of the gut-brain-axis. Also, in the activity-based anorexia (ABA) animal model mimicking AN brain...

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Bibliographic Details
Main Authors: Valerie Verspohl, Miranda van Egmond, Lilly Kneisel, Friederike Reese, Anna C. Thelen, Nele Korten, Maren Neumann, Lena Schaack, Clara Voelz, Larissa Käver, Beate Herpertz-Dahlmann, Cordian Beyer, Jochen Seitz, Stefanie Trinh
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-98237-z
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