Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus
Objective. To investigate the risk factors of DR in Chinese T2DM patients. Methods. 2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. Correlation analysis was performed to evaluate the rela...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/157940 |
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| author | Bin-Bin He Li Wei Yun-Juan Gu Jun-Feng Han Ming Li Yu-Xiang Liu Yu-Qian Bao Wei-Ping Jia |
| author_facet | Bin-Bin He Li Wei Yun-Juan Gu Jun-Feng Han Ming Li Yu-Xiang Liu Yu-Qian Bao Wei-Ping Jia |
| author_sort | Bin-Bin He |
| collection | DOAJ |
| description | Objective. To investigate the risk factors of DR in Chinese T2DM patients. Methods. 2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. Correlation analysis was performed to evaluate the relation between DR and clinical variables. Logistic regression models were used to assess risk for those factors associated with DR. Results. A total of 597 T2DM patients (29.7%) had DR, of which 548 (27.3%) were nonproliferative diabetic retinopathy and 49 (2.4%) were proliferative diabetic retinopathy. Positive correlations were found between DR and duration of diabetes, systolic blood pressure (SBP), diastolic blood pressure, glycated hemoglobin, glycated albumin, 24 hurinary albumin excretion, peripheral atherosclerosis (PA), diabetes nephropathy (DN), diabetic peripheral neuropathy, and anemia. Negative correlations were found between DR and C-peptide and glomerular filtration rate. Logistic regression analysis revealed that duration of diabetes, SBP, DN, anemia, PA, and C-peptide were each independent risk factors of DR. Conclusion. The duration of diabetes, SBP, DN, anemia, and PA are positively associated with DR in Chinese T2DM patients, while C-peptide is negatively associated with DR. Monitoring and evaluation of these related factors will likely contribute to the prevention and treatment of DR. |
| format | Article |
| id | doaj-art-702f7c93129e4582b1384f93e2fe3c7a |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-702f7c93129e4582b1384f93e2fe3c7a2025-02-03T05:45:14ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/157940157940Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes MellitusBin-Bin He0Li Wei1Yun-Juan Gu2Jun-Feng Han3Ming Li4Yu-Xiang Liu5Yu-Qian Bao6Wei-Ping Jia7Shanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaShanghai Municipal Key Laboratory on Diabetes, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, and Shanghai Municipal Clinical Center on Diabetes, Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, ChinaObjective. To investigate the risk factors of DR in Chinese T2DM patients. Methods. 2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. Correlation analysis was performed to evaluate the relation between DR and clinical variables. Logistic regression models were used to assess risk for those factors associated with DR. Results. A total of 597 T2DM patients (29.7%) had DR, of which 548 (27.3%) were nonproliferative diabetic retinopathy and 49 (2.4%) were proliferative diabetic retinopathy. Positive correlations were found between DR and duration of diabetes, systolic blood pressure (SBP), diastolic blood pressure, glycated hemoglobin, glycated albumin, 24 hurinary albumin excretion, peripheral atherosclerosis (PA), diabetes nephropathy (DN), diabetic peripheral neuropathy, and anemia. Negative correlations were found between DR and C-peptide and glomerular filtration rate. Logistic regression analysis revealed that duration of diabetes, SBP, DN, anemia, PA, and C-peptide were each independent risk factors of DR. Conclusion. The duration of diabetes, SBP, DN, anemia, and PA are positively associated with DR in Chinese T2DM patients, while C-peptide is negatively associated with DR. Monitoring and evaluation of these related factors will likely contribute to the prevention and treatment of DR.http://dx.doi.org/10.1155/2012/157940 |
| spellingShingle | Bin-Bin He Li Wei Yun-Juan Gu Jun-Feng Han Ming Li Yu-Xiang Liu Yu-Qian Bao Wei-Ping Jia Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus International Journal of Endocrinology |
| title | Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus |
| title_full | Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus |
| title_fullStr | Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus |
| title_full_unstemmed | Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus |
| title_short | Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus |
| title_sort | factors associated with diabetic retinopathy in chinese patients with type 2 diabetes mellitus |
| url | http://dx.doi.org/10.1155/2012/157940 |
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