Safety and efficacy of apatinib in combination treatment versus apatinib as second-line treatment for advanced gastric cancer

Safety and efficacy of apatinib in combination treatment versus apatinib as second-line treatment for advanced gastric cancer

BackgroundApatinib is a systemic therapeutic agent for advanced gastric adenocarcinoma (GAC) and gastroesophageal junction adenocarcinoma (GEJA). Its efficacy can be enhanced by applying it as a combination therapy, but the evidence supporting its combination application as a second-line treatment i...

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Bibliographic Details
Main Authors: Zhang Han, Zhu Yuanzeng, Wu Gang, Sun Peichun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
apatinib
combination treatment
efficacy
safety
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1587069/full
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