The haemagglutinin gene of bovine-origin H5N1 influenza viruses currently retains receptor-binding and pH-fusion characteristics of avian host phenotype

The haemagglutinin gene of bovine-origin H5N1 influenza viruses currently retains receptor-binding and pH-fusion characteristics of avian host phenotype

Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) has caused a panzootic affecting all continents except Australia, expanding its host range to several mammalian species. In March 2024, H5N1 HPAIV was first detected in dairy cattle and goats in the United States. Over 891 dairy fa...

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Bibliographic Details
Main Authors: Jiayun Yang, Mehnaz Qureshi, Reddy Kolli, Thomas P. Peacock, Jean-Remy Sadeyen, Toby Carter, Samuel Richardson, Rebecca Daines, Wendy S. Barclay, Ian H. Brown, Munir Iqbal
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
High pathogenicity avian influenza
cattle and goat H5N1
receptor binding
pH fusion
zoonotic risk
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2451052
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