Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)

Behcet’s disease (BD) — a systemic chronic idiopathic inflammatory recurrent disease of unknown etiology. The development of the disease involve a combination of various factors, among them the most important is genetic and infectious. Eye lesion is one of the most frequent and severe symptoms of Be...

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Main Authors: O. Yu. Yatsenko, O. S. Velibekova, A. I. Samoilenko, I. M. Tikhonova, I. G. Burdenko, E. N. Panina
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2016-12-01
Series:Oftalʹmologiâ
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Online Access:https://www.ophthalmojournal.com/opht/article/view/340
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author O. Yu. Yatsenko
O. S. Velibekova
A. I. Samoilenko
I. M. Tikhonova
I. G. Burdenko
E. N. Panina
author_facet O. Yu. Yatsenko
O. S. Velibekova
A. I. Samoilenko
I. M. Tikhonova
I. G. Burdenko
E. N. Panina
author_sort O. Yu. Yatsenko
collection DOAJ
description Behcet’s disease (BD) — a systemic chronic idiopathic inflammatory recurrent disease of unknown etiology. The development of the disease involve a combination of various factors, among them the most important is genetic and infectious. Eye lesion is one of the most frequent and severe symptoms of Behcet’s disease. According to the literature, eye lesion appears in 54–90% cases. There are several types of Behcet’s disease: the front, posterior and panuveitis, retinal vasculitis, occlusion of the branches of the central retinal vein, episcleritis, scleritis, keratitis, anterior ischemic neuropathy, paralysis of the extraocular muscles, swelling of the macula. In 95% cases the process is bilateral, but the clinical signs are often asymmetrical. Ocular pathology usually develops after 2–3 years the onset of symptoms BD. We havn’t met in the literature any case of Behcet’s disease, which has begun with hemophthalmia. Taking all these points together it seems to us interesting to present a clinical case of Behcet’s disease which has debuted with a bilateral hemophthalmus. This article describes a clinical case of Behcet’s disease in a patient of 38 years old. The interest of this observation is caused by feature of the appearance of clinical symptoms. Bilateral hemophthalmus has originally appeared, twice (in 2013 and 2014) and has been treated. During the next hospitalization the treatment has produced the positive effect was less  pronounced. After that, patient has undergone bilateral vitrectomy (2014). In April 2015 there were recurrent mouth ulcers, and 3 months later groin ulcers has appeared, pain in the joints. The ophthalmologist examination has shown commenmorative signs of left uveitis. The patient was counseled at the Institute of Rheumatology, where were determined the diagnosis of Behcet’s disease.This paper shows the clinical data and the results of additional tests (OCT, fluorescein angiography, ultrasonography), the results of blood biochemical examination and immune status.
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spelling doaj-art-7025c7a4449c44299cd93bb2d61cf2cf2025-08-20T02:56:15ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452016-12-0113428228910.18008/1816-5095-2016-4-282-289315Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)O. Yu. Yatsenko0O. S. Velibekova1A. I. Samoilenko2I. M. Tikhonova3I. G. Burdenko4E. N. Panina5”Russian Medical Academy of Postgraduate Education””Russian Medical Academy of Postgraduate Education”Moscow State Healthcare Institution ”City clinical hospital named S.P.Botkin”Moscow State Healthcare Institution ”City clinical hospital named S.P.Botkin”Moscow State Healthcare Institution ”City clinical hospital named S.P.Botkin”Moscow State Healthcare Institution ”City clinical hospital named S.P.Botkin”Behcet’s disease (BD) — a systemic chronic idiopathic inflammatory recurrent disease of unknown etiology. The development of the disease involve a combination of various factors, among them the most important is genetic and infectious. Eye lesion is one of the most frequent and severe symptoms of Behcet’s disease. According to the literature, eye lesion appears in 54–90% cases. There are several types of Behcet’s disease: the front, posterior and panuveitis, retinal vasculitis, occlusion of the branches of the central retinal vein, episcleritis, scleritis, keratitis, anterior ischemic neuropathy, paralysis of the extraocular muscles, swelling of the macula. In 95% cases the process is bilateral, but the clinical signs are often asymmetrical. Ocular pathology usually develops after 2–3 years the onset of symptoms BD. We havn’t met in the literature any case of Behcet’s disease, which has begun with hemophthalmia. Taking all these points together it seems to us interesting to present a clinical case of Behcet’s disease which has debuted with a bilateral hemophthalmus. This article describes a clinical case of Behcet’s disease in a patient of 38 years old. The interest of this observation is caused by feature of the appearance of clinical symptoms. Bilateral hemophthalmus has originally appeared, twice (in 2013 and 2014) and has been treated. During the next hospitalization the treatment has produced the positive effect was less  pronounced. After that, patient has undergone bilateral vitrectomy (2014). In April 2015 there were recurrent mouth ulcers, and 3 months later groin ulcers has appeared, pain in the joints. The ophthalmologist examination has shown commenmorative signs of left uveitis. The patient was counseled at the Institute of Rheumatology, where were determined the diagnosis of Behcet’s disease.This paper shows the clinical data and the results of additional tests (OCT, fluorescein angiography, ultrasonography), the results of blood biochemical examination and immune status.https://www.ophthalmojournal.com/opht/article/view/340behcet’s diseasehemophthalmusfluorescein angiographyvitrectomyulcer of the oral mucosa and groin area
spellingShingle O. Yu. Yatsenko
O. S. Velibekova
A. I. Samoilenko
I. M. Tikhonova
I. G. Burdenko
E. N. Panina
Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)
Oftalʹmologiâ
behcet’s disease
hemophthalmus
fluorescein angiography
vitrectomy
ulcer of the oral mucosa and groin area
title Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)
title_full Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)
title_fullStr Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)
title_full_unstemmed Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)
title_short Bilateral Hemophthalmus — the First Symptom of Behcet’s Disease (Clinical Case)
title_sort bilateral hemophthalmus the first symptom of behcet s disease clinical case
topic behcet’s disease
hemophthalmus
fluorescein angiography
vitrectomy
ulcer of the oral mucosa and groin area
url https://www.ophthalmojournal.com/opht/article/view/340
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AT aisamoilenko bilateralhemophthalmusthefirstsymptomofbehcetsdiseaseclinicalcase
AT imtikhonova bilateralhemophthalmusthefirstsymptomofbehcetsdiseaseclinicalcase
AT igburdenko bilateralhemophthalmusthefirstsymptomofbehcetsdiseaseclinicalcase
AT enpanina bilateralhemophthalmusthefirstsymptomofbehcetsdiseaseclinicalcase