Convergent evolution links molybdenum insertase domains with organism-specific sequences
Abstract In all domains of life, the biosynthesis of the pterin-based Molybdenum cofactor (Moco) is crucial. Molybdenum (Mo) becomes biologically active by integrating into a unique pyranopterin scaffold, forming Moco. The final two steps of Moco biosynthesis are catalyzed by the two-domain enzyme M...
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| Main Authors: | Miriam Rabenow, Eduard Haar, Katharina Schmidt, Robert Hänsch, Ralf R. Mendel, Kevin D. Oliphant |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-024-07073-w |
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