Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report

Breast cancer in men is uncommon, and even more rare is the simultaneous presentation of two different malignancies. A 39-year-old man was diagnosed with both breast cancer and axillary lymphoma. Familiar history revealed that his mother died because of breast cancer. The patient underwent fine need...

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Main Authors: Emiliano Sordi, Katia Cagossi, Maria Grazia Lazzaretti, Daniel Gusolfino, Fabrizio Artioli, Giovanni Santacroce, Maria Luisa Brandi, Prisco Piscitelli
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/940803
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author Emiliano Sordi
Katia Cagossi
Maria Grazia Lazzaretti
Daniel Gusolfino
Fabrizio Artioli
Giovanni Santacroce
Maria Luisa Brandi
Prisco Piscitelli
author_facet Emiliano Sordi
Katia Cagossi
Maria Grazia Lazzaretti
Daniel Gusolfino
Fabrizio Artioli
Giovanni Santacroce
Maria Luisa Brandi
Prisco Piscitelli
author_sort Emiliano Sordi
collection DOAJ
description Breast cancer in men is uncommon, and even more rare is the simultaneous presentation of two different malignancies. A 39-year-old man was diagnosed with both breast cancer and axillary lymphoma. Familiar history revealed that his mother died because of breast cancer. The patient underwent fine needle aspiration leading to the diagnosis of malignant lesion. Modified radical mastectomy was performed. Histology revealed an infiltrating ductal carcinoma 2.8 cm wide, grade 2, with vascular and lymphatic invasion. Surprisingly, one of the second level nodes was confirmed as a high-grade large B cell non-Hodgkin's lymphoma. No family inheritance or gene mutations (BRCA 1 and 2) were found. The patient underwent local radiotherapy, followed by 6 chemotherapy courses (RCHOP) and treatment with tamoxifen 20 mg/daily. To our knowledge, this is the first case reported in literature of male breast cancer and axillary lymphoma simultaneously confirmed in the same patient.
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spelling doaj-art-70185c6b25f446daaeeff357a6c502fc2025-08-20T02:06:15ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/940803940803Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case ReportEmiliano Sordi0Katia Cagossi1Maria Grazia Lazzaretti2Daniel Gusolfino3Fabrizio Artioli4Giovanni Santacroce5Maria Luisa Brandi6Prisco Piscitelli7Ramazzini Hospital, Division of Oncology, 41012 Carpi, ItalyRamazzini Hospital, Division of Oncology, 41012 Carpi, ItalyRamazzini Hospital, Division of Oncology, 41012 Carpi, ItalyRamazzini Hospital, Division of Oncology, 41012 Carpi, ItalyRamazzini Hospital, Division of Oncology, 41012 Carpi, ItalyLocal Health Authority ASL Lecce, Division of Oncology, 73048 Nardò, ItalyUniversity of Florence, Department of Internal Medicine, 50139 Florence, ItalyUniversity of Florence, Department of Internal Medicine, 50139 Florence, ItalyBreast cancer in men is uncommon, and even more rare is the simultaneous presentation of two different malignancies. A 39-year-old man was diagnosed with both breast cancer and axillary lymphoma. Familiar history revealed that his mother died because of breast cancer. The patient underwent fine needle aspiration leading to the diagnosis of malignant lesion. Modified radical mastectomy was performed. Histology revealed an infiltrating ductal carcinoma 2.8 cm wide, grade 2, with vascular and lymphatic invasion. Surprisingly, one of the second level nodes was confirmed as a high-grade large B cell non-Hodgkin's lymphoma. No family inheritance or gene mutations (BRCA 1 and 2) were found. The patient underwent local radiotherapy, followed by 6 chemotherapy courses (RCHOP) and treatment with tamoxifen 20 mg/daily. To our knowledge, this is the first case reported in literature of male breast cancer and axillary lymphoma simultaneously confirmed in the same patient.http://dx.doi.org/10.1155/2011/940803
spellingShingle Emiliano Sordi
Katia Cagossi
Maria Grazia Lazzaretti
Daniel Gusolfino
Fabrizio Artioli
Giovanni Santacroce
Maria Luisa Brandi
Prisco Piscitelli
Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report
Case Reports in Medicine
title Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report
title_full Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report
title_fullStr Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report
title_full_unstemmed Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report
title_short Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report
title_sort rare case of male breast cancer and axillary lymphoma in the same patient an unique case report
url http://dx.doi.org/10.1155/2011/940803
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