Primary Synovial Sarcoma of the Mediastinum : A Case Report
Synovial sarcomas commonly occur in the extremities of young adults. A primary occurrence in the mediastinum is very rare with only a few reported cases in the world literature. This paper is about a 42-year-old male who presented with chest pain and dyspnoea on exertion. Imaging showed an anteri...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2011/602853 |
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| Summary: | Synovial sarcomas commonly occur in the extremities of young adults. A primary
occurrence in the mediastinum is very rare with only a few reported cases in the
world literature. This paper is about a 42-year-old male who presented with
chest pain and dyspnoea on exertion. Imaging showed an anterior mediastinal
mass with adhesions to the lung. Pathological examination of the resected mass
showed a biphasic neoplasm with a spindle cell component admixed with gland-like elements. The tumour showed positive staining with cytokeratin, epithelial
membrane antigen, and Bcl-2 confirming the diagnosis of a biphasic synovial
sarcoma. A wide range of neoplasms, both primary and metastatic, occur in the
mediastinum, which pose considerable diagnostic difficulties. A synovial sarcoma
should always be considered in the differential diagnosis, and
immunohistochemistry is an important adjuvant tool in this situation. This paper highlights the importance of recognizing an unusual presentation of this
aggressive neoplasm to aid appropriate clinical management. |
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| ISSN: | 2090-6900 2090-6919 |