Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis

uvenile idiopathic arthritis (JIA) belongs to a heterogeneous group of chronic inflammatory joint diseases in children, which begin under 16, tend to progressive joint disease involving synovium with chondrolysis, destruction of bone structures, and often formation of ankylosis.To reveal structural...

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Main Authors: V. O. Roschina, V. D. Zavadovskaya, N. G. Zaviyalova, A. N. Kailina, Yu. P. Chasovskikh
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2012-10-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/611
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author V. O. Roschina
V. D. Zavadovskaya
N. G. Zaviyalova
A. N. Kailina
Yu. P. Chasovskikh
author_facet V. O. Roschina
V. D. Zavadovskaya
N. G. Zaviyalova
A. N. Kailina
Yu. P. Chasovskikh
author_sort V. O. Roschina
collection DOAJ
description uvenile idiopathic arthritis (JIA) belongs to a heterogeneous group of chronic inflammatory joint diseases in children, which begin under 16, tend to progressive joint disease involving synovium with chondrolysis, destruction of bone structures, and often formation of ankylosis.To reveal structural changes in knee joints, 25 children with JIA were passed through ultrasonic examination with the use of 7.5—11 (14) MHz linear sensors in superscale mode with energy and color Doppler mapping. Standard laboratory indices, rheumatoid factor (RF), and modified citrullinated vimentin antibodies (MCVA) in blood serum by the ELISA method were determined as well. The JIA activity was assessed using the DAS28 index. In the examination of knee joints in the group with JIA, most characteristic changes were uniform synovium thickening (68% of cases) with proliferation and vascularization (in 50% at proliferation), joint capsule effusion (56% cases) with mean values of (4.16 ± 2.47) mm. Reliable correlation has been revealed between synovium vascularization and MCVA level, erythrocyte sedimentation rate, and DAS28 activity, as well as thickness of joint effusion with MCVA level.
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spelling doaj-art-70116b8dbdac469a9de2b8973f7c33dd2025-08-20T03:02:23ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-10-01115162210.20538/1682-0363-2012-5-16-22556Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritisV. O. Roschina0V. D. Zavadovskaya1N. G. Zaviyalova2A. N. Kailina3Yu. P. Chasovskikh4МБЛПУ «Детская городская больница № 1», г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. Томскuvenile idiopathic arthritis (JIA) belongs to a heterogeneous group of chronic inflammatory joint diseases in children, which begin under 16, tend to progressive joint disease involving synovium with chondrolysis, destruction of bone structures, and often formation of ankylosis.To reveal structural changes in knee joints, 25 children with JIA were passed through ultrasonic examination with the use of 7.5—11 (14) MHz linear sensors in superscale mode with energy and color Doppler mapping. Standard laboratory indices, rheumatoid factor (RF), and modified citrullinated vimentin antibodies (MCVA) in blood serum by the ELISA method were determined as well. The JIA activity was assessed using the DAS28 index. In the examination of knee joints in the group with JIA, most characteristic changes were uniform synovium thickening (68% of cases) with proliferation and vascularization (in 50% at proliferation), joint capsule effusion (56% cases) with mean values of (4.16 ± 2.47) mm. Reliable correlation has been revealed between synovium vascularization and MCVA level, erythrocyte sedimentation rate, and DAS28 activity, as well as thickness of joint effusion with MCVA level.https://bulletin.ssmu.ru/jour/article/view/611juvenile idiopathic arthritismodified citrullinated vimentin antibodiesrheumatoid factorultrasonography of knee joints
spellingShingle V. O. Roschina
V. D. Zavadovskaya
N. G. Zaviyalova
A. N. Kailina
Yu. P. Chasovskikh
Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
Бюллетень сибирской медицины
juvenile idiopathic arthritis
modified citrullinated vimentin antibodies
rheumatoid factor
ultrasonography of knee joints
title Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
title_full Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
title_fullStr Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
title_full_unstemmed Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
title_short Role of ultrasonic examination in assessment of the knee-joint state in patients with juvenile idiopathic arthritis
title_sort role of ultrasonic examination in assessment of the knee joint state in patients with juvenile idiopathic arthritis
topic juvenile idiopathic arthritis
modified citrullinated vimentin antibodies
rheumatoid factor
ultrasonography of knee joints
url https://bulletin.ssmu.ru/jour/article/view/611
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AT ngzaviyalova roleofultrasonicexaminationinassessmentofthekneejointstateinpatientswithjuvenileidiopathicarthritis
AT ankailina roleofultrasonicexaminationinassessmentofthekneejointstateinpatientswithjuvenileidiopathicarthritis
AT yupchasovskikh roleofultrasonicexaminationinassessmentofthekneejointstateinpatientswithjuvenileidiopathicarthritis