Genetic analysis of comorbidities between osteoarthritis, sarcopenia, and osteoporosis

Genetic analysis of comorbidities between osteoarthritis, sarcopenia, and osteoporosis

Background: Osteoarthritis (OA), sarcopenia (SCP), and osteoporosis (OP) pose a substantial global morbidity and mortality burden, and previous studies have observed potential associations among them. This study aims to comprehensively characterize the common genetic structure, biological basis, and...

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Bibliographic Details
Main Authors: Zhi Liu, XiangMing Chen, Zhe Ruan, Chao Wang, Dongliang Yuan, Wenfeng Xiao, Yusheng Li, Shushan Zhao
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Experimental Gerontology
Subjects:
Osteoarthritis
Sarcopenia
Osteoporosis
Genetic correlation
Shared genetic structure
Causal association
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525001172
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