SOX9 plays an essential role in myofibroblast driven hepatic granuloma integrity and parenchymal repair during schistosomiasis-induced liver damage.

Schistosomiasis is a neglected, and potentially lethal, parasitic disease that affects hundreds of millions of people worldwide. As part of the schistosome lifecycle, parasite eggs accumulate within the liver where they evoke intense granulomatous pathology, typified by a dense extracellular matrix...

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Bibliographic Details
Main Authors: Kim Su, Elliot Jokl, Alice Costain, Kara Simpson, Antonn Cheeseman, Alexander Phythian-Adams, Kevin N Couper, Andrew S MacDonald, Karen Piper Hanley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012928
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