Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults
Objective: The aim of this study was to assess the relationship between basal metabolic rate (BMR) and all-cause mortality in southern Chinese adults.Methods: We prospectively examined the relationship between BMR and all-cause mortality in 12,608 Southern Chinese adults with age ≥ 35 years who part...
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Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.790347/full |
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| author | Fengyu Han Fengyu Han Feng Hu Feng Hu Tao Wang Tao Wang Wei Zhou Wei Zhou Linjuan Zhu Linjuan Zhu Xiao Huang Xiao Huang Xiao Huang Huihui Bao Huihui Bao Huihui Bao Xiaoshu Cheng Xiaoshu Cheng Xiaoshu Cheng |
| author_facet | Fengyu Han Fengyu Han Feng Hu Feng Hu Tao Wang Tao Wang Wei Zhou Wei Zhou Linjuan Zhu Linjuan Zhu Xiao Huang Xiao Huang Xiao Huang Huihui Bao Huihui Bao Huihui Bao Xiaoshu Cheng Xiaoshu Cheng Xiaoshu Cheng |
| author_sort | Fengyu Han |
| collection | DOAJ |
| description | Objective: The aim of this study was to assess the relationship between basal metabolic rate (BMR) and all-cause mortality in southern Chinese adults.Methods: We prospectively examined the relationship between BMR and all-cause mortality in 12,608 Southern Chinese adults with age ≥ 35 years who participated in the National Key R&D Program from 2013–2014 to 2019–2020. Cox proportional hazard models were used to examine the association between BMR and all-cause mortality.Results: A total of 809 deaths (including 478 men and 331 women) occurred during a median follow-up period of 5.60 years. All-cause mortality was higher in elderly individuals than in non-elderly individuals (11.48 vs. 2.04%, P < 0.001) and was higher in male subjects than in female subjects (9.84 vs. 4.56%, P < 0.001). There was a significantly inverse relationship between BMR levels and all-cause mortality in elderly male individuals (adjusted-HR per SD increase: 0.80, 95% CI: 0.70–0.91, P < 0.001). Compared with BMR levels ≤ 1,115 kcal/day, there was lower all-cause mortality in third and highest BMR quartiles in the elderly male subjects (adjusted-HR: 0.71, 95% CI: 0.53–0.95, P = 0.022; adjusted-HR: 0.60, 95% CI: 0.43–0.84, P = 0.003, respectively).Conclusion: An elevated BMR was independently inversely associated with all-cause mortality in elderly male subjects in a southern Chinese population. |
| format | Article |
| id | doaj-art-7001e8c41d394c1fbea920185b49b26a |
| institution | DOAJ |
| issn | 1664-042X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj-art-7001e8c41d394c1fbea920185b49b26a2025-08-20T03:10:24ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2022-01-011210.3389/fphys.2021.790347790347Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese AdultsFengyu Han0Fengyu Han1Feng Hu2Feng Hu3Tao Wang4Tao Wang5Wei Zhou6Wei Zhou7Linjuan Zhu8Linjuan Zhu9Xiao Huang10Xiao Huang11Xiao Huang12Huihui Bao13Huihui Bao14Huihui Bao15Xiaoshu Cheng16Xiaoshu Cheng17Xiaoshu Cheng18The Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaThe Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaThe Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaThe Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaThe Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaJiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, Nanchang, ChinaCenter for Prevention and Treatment of Cardiovascular Diseases, The Second Affiliated Hospital of Nanchang University, Nanchang, ChinaObjective: The aim of this study was to assess the relationship between basal metabolic rate (BMR) and all-cause mortality in southern Chinese adults.Methods: We prospectively examined the relationship between BMR and all-cause mortality in 12,608 Southern Chinese adults with age ≥ 35 years who participated in the National Key R&D Program from 2013–2014 to 2019–2020. Cox proportional hazard models were used to examine the association between BMR and all-cause mortality.Results: A total of 809 deaths (including 478 men and 331 women) occurred during a median follow-up period of 5.60 years. All-cause mortality was higher in elderly individuals than in non-elderly individuals (11.48 vs. 2.04%, P < 0.001) and was higher in male subjects than in female subjects (9.84 vs. 4.56%, P < 0.001). There was a significantly inverse relationship between BMR levels and all-cause mortality in elderly male individuals (adjusted-HR per SD increase: 0.80, 95% CI: 0.70–0.91, P < 0.001). Compared with BMR levels ≤ 1,115 kcal/day, there was lower all-cause mortality in third and highest BMR quartiles in the elderly male subjects (adjusted-HR: 0.71, 95% CI: 0.53–0.95, P = 0.022; adjusted-HR: 0.60, 95% CI: 0.43–0.84, P = 0.003, respectively).Conclusion: An elevated BMR was independently inversely associated with all-cause mortality in elderly male subjects in a southern Chinese population.https://www.frontiersin.org/articles/10.3389/fphys.2021.790347/fullbasal metabolic rateall-cause mortalityChineseadultsaging |
| spellingShingle | Fengyu Han Fengyu Han Feng Hu Feng Hu Tao Wang Tao Wang Wei Zhou Wei Zhou Linjuan Zhu Linjuan Zhu Xiao Huang Xiao Huang Xiao Huang Huihui Bao Huihui Bao Huihui Bao Xiaoshu Cheng Xiaoshu Cheng Xiaoshu Cheng Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults Frontiers in Physiology basal metabolic rate all-cause mortality Chinese adults aging |
| title | Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults |
| title_full | Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults |
| title_fullStr | Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults |
| title_full_unstemmed | Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults |
| title_short | Association Between Basal Metabolic Rate and All-Cause Mortality in a Prospective Cohort of Southern Chinese Adults |
| title_sort | association between basal metabolic rate and all cause mortality in a prospective cohort of southern chinese adults |
| topic | basal metabolic rate all-cause mortality Chinese adults aging |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2021.790347/full |
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