Smooth muscle-specific expression of hydroxyindole O-methyltransferase reduces arterial injury-induced intimal hyperplasia
Abstract Background The pineal gland produces melatonin to control circadian rhythm via the final enzyme in the serotonin pathway, hydroxyindole O-methyltransferase (HIOMT). Interestingly, HIOMT is expressed by certain non-pineal cells. The main catalytically active of the three human HIOMT (hHIOMT)...
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| Main Authors: | Wei-Cheng Jiang, Chung-Huang Chen, Hua-Hui Ho, Pei-Yu Gung, Jing-Yiing Wu, Cheng-Chin Kuo, Kenneth K. Wu, Shaw-Fang Yet |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | Journal of Biomedical Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12929-025-01172-4 |
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