Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and adolescents. It arises from primitive mesenchymal cells that typically differentiate into skeletal muscle tissue. The causes and risk factors are not well understood, and most cases are sporadic, although some are linked t...
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JCDR Research and Publications Private Limited
2025-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/21137/78792_CE[Ra1]_F(IS)_PF1(KA_OM)_redo_PFA_NC(IS)_PB(KA_IS)_PN(IS).pdf |
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| _version_ | 1849424605868982272 |
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| author | Apurva Jarandikar Priya Elangbam Mayur Ingale |
| author_facet | Apurva Jarandikar Priya Elangbam Mayur Ingale |
| author_sort | Apurva Jarandikar |
| collection | DOAJ |
| description | Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and adolescents. It arises from primitive mesenchymal cells that typically differentiate into skeletal muscle tissue. The causes and risk factors are not well understood, and most cases are sporadic, although some are linked to familial syndromes. A 10-year-old female patient presented with swelling on the left-side of her face. Following a wedge biopsy and histopathological and immunohistochemical analyses confirmed Embryonal Rhabdomyosarcoma (ERMS). Treatment involved a multimodal approach, combining surgical removal of the primary tumour, chemotherapy to address potential micro metastases, and radiotherapy for patients at higher risk. Improved survival rates are attributed to collaborative care and advancements in diagnosis and treatment. This case underscores the importance of coordinated care for timely diagnosis and effective treatment, leading to better patient outcomes and reduced morbidity. |
| format | Article |
| id | doaj-art-6fe77a885149405b82aa111c111456d0 |
| institution | Kabale University |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-6fe77a885149405b82aa111c111456d02025-08-20T03:30:04ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-06-01195MD01MD0310.7860/JCDR/2025/78792.21137Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case ReportApurva Jarandikar0Priya Elangbam1Mayur Ingale2Assistant Professor, Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharastra, India.Resident, Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharastra, India.Professor, Department of ENT, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharastra, India.Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and adolescents. It arises from primitive mesenchymal cells that typically differentiate into skeletal muscle tissue. The causes and risk factors are not well understood, and most cases are sporadic, although some are linked to familial syndromes. A 10-year-old female patient presented with swelling on the left-side of her face. Following a wedge biopsy and histopathological and immunohistochemical analyses confirmed Embryonal Rhabdomyosarcoma (ERMS). Treatment involved a multimodal approach, combining surgical removal of the primary tumour, chemotherapy to address potential micro metastases, and radiotherapy for patients at higher risk. Improved survival rates are attributed to collaborative care and advancements in diagnosis and treatment. This case underscores the importance of coordinated care for timely diagnosis and effective treatment, leading to better patient outcomes and reduced morbidity.https://jcdr.net/articles/PDF/21137/78792_CE[Ra1]_F(IS)_PF1(KA_OM)_redo_PFA_NC(IS)_PB(KA_IS)_PN(IS).pdfchemotherapyembryonal typeimmunohistochemistryskeletal muscle tumour |
| spellingShingle | Apurva Jarandikar Priya Elangbam Mayur Ingale Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report Journal of Clinical and Diagnostic Research chemotherapy embryonal type immunohistochemistry skeletal muscle tumour |
| title | Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report |
| title_full | Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report |
| title_fullStr | Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report |
| title_full_unstemmed | Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report |
| title_short | Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report |
| title_sort | multidisciplinary approach in management of rhabdomyosarcoma of the face a rare case report |
| topic | chemotherapy embryonal type immunohistochemistry skeletal muscle tumour |
| url | https://jcdr.net/articles/PDF/21137/78792_CE[Ra1]_F(IS)_PF1(KA_OM)_redo_PFA_NC(IS)_PB(KA_IS)_PN(IS).pdf |
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