Multidisciplinary Approach in Management of Rhabdomyosarcoma of the Face: A Rare Case Report
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and adolescents. It arises from primitive mesenchymal cells that typically differentiate into skeletal muscle tissue. The causes and risk factors are not well understood, and most cases are sporadic, although some are linked t...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2025-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/21137/78792_CE[Ra1]_F(IS)_PF1(KA_OM)_redo_PFA_NC(IS)_PB(KA_IS)_PN(IS).pdf |
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| Summary: | Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children and adolescents. It arises from primitive mesenchymal cells that typically differentiate into skeletal muscle tissue. The causes and risk factors are not well understood, and most cases are sporadic, although some are linked to familial syndromes. A 10-year-old female patient presented with swelling on the left-side of her face. Following a wedge biopsy and histopathological and immunohistochemical analyses confirmed Embryonal Rhabdomyosarcoma (ERMS). Treatment involved a multimodal approach, combining surgical removal of the primary tumour, chemotherapy to address potential micro metastases, and radiotherapy for patients at higher risk. Improved survival rates are attributed to collaborative care and advancements in diagnosis and treatment. This case underscores the importance of coordinated care for timely diagnosis and effective treatment, leading to better patient outcomes and reduced morbidity. |
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| ISSN: | 2249-782X 0973-709X |