Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data
A first data set refers to tissue inhibitor of matrix metalloprotease-1 (TIMP-1) protein inclusion into a DegraPol® fibres utilizing emulsion electrospinning and the characterization of the random fibre mesh. Specifically, the release kinetics of the protein from the mesh was studied over 7 days. Mo...
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Elsevier
2025-06-01
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| author | Julia Rieber Roger Khalid Niederhauser Pietro Giovanoli Johanna Buschmann |
| author_facet | Julia Rieber Roger Khalid Niederhauser Pietro Giovanoli Johanna Buschmann |
| author_sort | Julia Rieber |
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| description | A first data set refers to tissue inhibitor of matrix metalloprotease-1 (TIMP-1) protein inclusion into a DegraPol® fibres utilizing emulsion electrospinning and the characterization of the random fibre mesh. Specifically, the release kinetics of the protein from the mesh was studied over 7 days. Moreover, the static and the dynamic water contact angles were determined. Finally, we assessed Fourier-Transformed Infrared Spectra (FTIR spectra) for DegraPol® with and without TIMP-1.A second data set represents proliferation data obtained with the Alamar Blue Assay, applied on rabbit Achilles tenocytes and rabbit adipose-derived stem cells, when stimulated in vitro with 1, 10, and 100 ng/mL TIMP-1 supplementation compared to the corresponding cell culture without TIMP-1 (control). Furthermore, qPCR was performed and collagen I, ki67, tenomodulin and alkaline phosphatase gene expression data are presented for both cell types in vitro stimulated with 1, 10, and 100 ng/mL TIMP-1 supplementation, respectively, and data are presented as manifold induction compared to a TIMP-1-free cell culture medium (control). |
| format | Article |
| id | doaj-art-6fd3300d8afc4785a9d00906bfdaf5ae |
| institution | DOAJ |
| issn | 2352-3409 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj-art-6fd3300d8afc4785a9d00906bfdaf5ae2025-08-20T03:10:41ZengElsevierData in Brief2352-34092025-06-016011146810.1016/j.dib.2025.111468Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley DataJulia Rieber0Roger Khalid Niederhauser1Pietro Giovanoli2Johanna Buschmann3Division of Plastic Surgery and Hand Surgery, Sternwartstrasse 14, University Hospital Zurich, Zurich 8091, SwitzerlandDivision of Plastic Surgery and Hand Surgery, Sternwartstrasse 14, University Hospital Zurich, Zurich 8091, SwitzerlandDivision of Plastic Surgery and Hand Surgery, Sternwartstrasse 14, University Hospital Zurich, Zurich 8091, SwitzerlandCorresponding author.; Division of Plastic Surgery and Hand Surgery, Sternwartstrasse 14, University Hospital Zurich, Zurich 8091, SwitzerlandA first data set refers to tissue inhibitor of matrix metalloprotease-1 (TIMP-1) protein inclusion into a DegraPol® fibres utilizing emulsion electrospinning and the characterization of the random fibre mesh. Specifically, the release kinetics of the protein from the mesh was studied over 7 days. Moreover, the static and the dynamic water contact angles were determined. Finally, we assessed Fourier-Transformed Infrared Spectra (FTIR spectra) for DegraPol® with and without TIMP-1.A second data set represents proliferation data obtained with the Alamar Blue Assay, applied on rabbit Achilles tenocytes and rabbit adipose-derived stem cells, when stimulated in vitro with 1, 10, and 100 ng/mL TIMP-1 supplementation compared to the corresponding cell culture without TIMP-1 (control). Furthermore, qPCR was performed and collagen I, ki67, tenomodulin and alkaline phosphatase gene expression data are presented for both cell types in vitro stimulated with 1, 10, and 100 ng/mL TIMP-1 supplementation, respectively, and data are presented as manifold induction compared to a TIMP-1-free cell culture medium (control).http://www.sciencedirect.com/science/article/pii/S2352340925002008Tissue inhibitor of matrix metalloprotease-1Water contact angleHydrophobicityRabbit Achilles tenocytesRabbit adipose-derived stem cells collagen type Iki67 |
| spellingShingle | Julia Rieber Roger Khalid Niederhauser Pietro Giovanoli Johanna Buschmann Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data Data in Brief Tissue inhibitor of matrix metalloprotease-1 Water contact angle Hydrophobicity Rabbit Achilles tenocytes Rabbit adipose-derived stem cells collagen type I ki67 |
| title | Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data |
| title_full | Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data |
| title_fullStr | Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data |
| title_full_unstemmed | Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data |
| title_short | Release kinetics, static and dynamic water contact angles and FTIR data for tissue inhibitor of matrix metalloprotease-1 (TIMP-1) incorporated in electrospun random DegraPol® fibers and TIMP-1 impact on tenocytes and adipose-derived stem cells proliferation and gene expression dataMendeley DataMendeley Data |
| title_sort | release kinetics static and dynamic water contact angles and ftir data for tissue inhibitor of matrix metalloprotease 1 timp 1 incorporated in electrospun random degrapol r fibers and timp 1 impact on tenocytes and adipose derived stem cells proliferation and gene expression datamendeley datamendeley data |
| topic | Tissue inhibitor of matrix metalloprotease-1 Water contact angle Hydrophobicity Rabbit Achilles tenocytes Rabbit adipose-derived stem cells collagen type I ki67 |
| url | http://www.sciencedirect.com/science/article/pii/S2352340925002008 |
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