THUMPD3 regulates alternative splicing of ECM transcripts in human lung cancer cells and promotes proliferation and migration.
RNA-modifying enzymes have recently garnered considerable attention due to their relevance in cancer biology, identifying them as potential targets for novel therapeutic intervention. THUMPD3 was recently identified as an RNA methyltransferase catalysing N2-methylguanosine (m2G) within certain tRNAs...
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| Main Authors: | Marie Klimontova, Han Zhang, Francisco Campos-Laborie, Natalie Webster, Byron Andrews, Kimberley Chung Kim Chung, Ryan Hili, Tony Kouzarides, Andrew J Bannister |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0314655 |
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