Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province

Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal cancers in Hebei province. Most patients are diagnosed at an advanced stage due to untypical early symptoms, making surgical treatment often unfeasible. As a result, most of them are treated with comprehensive me...

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Main Authors: Xiaoyang DUAN, Jian SHI
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-02-01
Series:Zhongliu Fangzhi Yanjiu
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Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.0856
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author Xiaoyang DUAN
Jian SHI
author_facet Xiaoyang DUAN
Jian SHI
author_sort Xiaoyang DUAN
collection DOAJ
description Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal cancers in Hebei province. Most patients are diagnosed at an advanced stage due to untypical early symptoms, making surgical treatment often unfeasible. As a result, most of them are treated with comprehensive medical treatment, which tends to have limited effectiveness and poor prognosis. However, the recent introduction of immunotherapy has considerably advanced treatment options for patients with advanced ESCC, notably improving their prognosis. Uncertainties regarding immune resistance, the selection of predictive indicators of efficacy, the identification of dominant population, and the choice of combined treatment strategies are still evident. Therefore, based on the high incidence and poor prognosis of ESCC in Hebei Province, this article will briefly review the research progress in the treatment of advanced ESCC, aiming to provide guidance for treatment strategies for advanced esophageal cancer.
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publisher Magazine House of Cancer Research on Prevention and Treatment
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series Zhongliu Fangzhi Yanjiu
spelling doaj-art-6fc50a5954ed458b95d9afaa112ef8452025-08-20T02:45:37ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782025-02-0152210310910.3971/j.issn.1000-8578.2025.24.085620240856Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei ProvinceXiaoyang DUAN0Jian SHI1Department of Medical Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, ChinaDepartment of Medical Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, ChinaEsophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal cancers in Hebei province. Most patients are diagnosed at an advanced stage due to untypical early symptoms, making surgical treatment often unfeasible. As a result, most of them are treated with comprehensive medical treatment, which tends to have limited effectiveness and poor prognosis. However, the recent introduction of immunotherapy has considerably advanced treatment options for patients with advanced ESCC, notably improving their prognosis. Uncertainties regarding immune resistance, the selection of predictive indicators of efficacy, the identification of dominant population, and the choice of combined treatment strategies are still evident. Therefore, based on the high incidence and poor prognosis of ESCC in Hebei Province, this article will briefly review the research progress in the treatment of advanced ESCC, aiming to provide guidance for treatment strategies for advanced esophageal cancer.http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.0856esophageal squamous cell carcinomaimmunotherapyresearch progress
spellingShingle Xiaoyang DUAN
Jian SHI
Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province
Zhongliu Fangzhi Yanjiu
esophageal squamous cell carcinoma
immunotherapy
research progress
title Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province
title_full Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province
title_fullStr Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province
title_full_unstemmed Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province
title_short Research Status and Progress on Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma in Hebei Province
title_sort research status and progress on immunotherapy for advanced esophageal squamous cell carcinoma in hebei province
topic esophageal squamous cell carcinoma
immunotherapy
research progress
url http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.0856
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