Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups
The asymmetric ligand (E)-4-bromo-2-(((2-((5-bromo-2-hydroxybenzyl)(methyl)amino)ethyl)imino)methyl)phenol has been prepared by a novel seven-step route. All organic compounds isolated in each step have been characterised by elemental analysis, infrared and 1H NMR spectroscopy, and mass spectrometry...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2015/963152 |
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| author | Yolanda Pérez-Otero M. Isabel Fernández-García Esther Gómez-Fórneas Gustavo González-Riopedre Marcelino Maneiro |
| author_facet | Yolanda Pérez-Otero M. Isabel Fernández-García Esther Gómez-Fórneas Gustavo González-Riopedre Marcelino Maneiro |
| author_sort | Yolanda Pérez-Otero |
| collection | DOAJ |
| description | The asymmetric ligand (E)-4-bromo-2-(((2-((5-bromo-2-hydroxybenzyl)(methyl)amino)ethyl)imino)methyl)phenol has been prepared by a novel seven-step route. All organic compounds isolated in each step have been characterised by elemental analysis, infrared and 1H NMR spectroscopy, and mass spectrometry. Interaction of this ligand with manganese has been investigated employing an electrochemical method. This method leads to the formation of a neutral manganese(II) complex 7 in high yield and purity. The complex has been thoroughly characterised by elemental analysis, infrared spectroscopy, mass spectrometry, magnetic susceptibility measurements, and cyclic voltammetry. Complex 7 behaves as peroxidase mimic in the presence of the water-soluble trap ABTS, probably due to its ease to coordinate the substrate molecule. |
| format | Article |
| id | doaj-art-6fc1c7f4c3704dabb3da059e10aa3913 |
| institution | OA Journals |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-6fc1c7f4c3704dabb3da059e10aa39132025-08-20T02:06:15ZengWileyJournal of Chemistry2090-90632090-90712015-01-01201510.1155/2015/963152963152Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino GroupsYolanda Pérez-Otero0M. Isabel Fernández-García1Esther Gómez-Fórneas2Gustavo González-Riopedre3Marcelino Maneiro4Departamento de Química Inorgánica, Facultad de Ciencias, Universidade de Santiago de Compostela, 27002 Lugo, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidade de Santiago de Compostela, 27002 Lugo, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidade de Santiago de Compostela, 27002 Lugo, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidade de Santiago de Compostela, 27002 Lugo, SpainDepartamento de Química Inorgánica, Facultad de Ciencias, Universidade de Santiago de Compostela, 27002 Lugo, SpainThe asymmetric ligand (E)-4-bromo-2-(((2-((5-bromo-2-hydroxybenzyl)(methyl)amino)ethyl)imino)methyl)phenol has been prepared by a novel seven-step route. All organic compounds isolated in each step have been characterised by elemental analysis, infrared and 1H NMR spectroscopy, and mass spectrometry. Interaction of this ligand with manganese has been investigated employing an electrochemical method. This method leads to the formation of a neutral manganese(II) complex 7 in high yield and purity. The complex has been thoroughly characterised by elemental analysis, infrared spectroscopy, mass spectrometry, magnetic susceptibility measurements, and cyclic voltammetry. Complex 7 behaves as peroxidase mimic in the presence of the water-soluble trap ABTS, probably due to its ease to coordinate the substrate molecule.http://dx.doi.org/10.1155/2015/963152 |
| spellingShingle | Yolanda Pérez-Otero M. Isabel Fernández-García Esther Gómez-Fórneas Gustavo González-Riopedre Marcelino Maneiro Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups Journal of Chemistry |
| title | Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups |
| title_full | Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups |
| title_fullStr | Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups |
| title_full_unstemmed | Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups |
| title_short | Mimicking Peroxidase Activity by a Manganese(II) Complex Involving a New Asymmetric Tetradentate Ligand Containing Both Amino and Imino Groups |
| title_sort | mimicking peroxidase activity by a manganese ii complex involving a new asymmetric tetradentate ligand containing both amino and imino groups |
| url | http://dx.doi.org/10.1155/2015/963152 |
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