Analysis of shared pathogenic mechanisms and drug targets in myocardial infarction and gastric cancer based on transcriptomics and machine learning

Analysis of shared pathogenic mechanisms and drug targets in myocardial infarction and gastric cancer based on transcriptomics and machine learning

BackgroundRecent studies have suggested a potential association between gastric cancer (GC) and myocardial infarction (MI), with shared pathogenic factors. This study aimed to identify these common factors and potential pharmacologic targets.MethodsData from the IEU Open GWAS project were used. Two-...

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Bibliographic Details
Main Authors: Junyang Ma, Shufu Hou, Xinxin Gu, Peng Guo, Jiankang Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
gastric cancer
myocardial infarction
Mendelian randomization
machine learning
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1533959/full
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