Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass
Posttransplant lymphoproliferative disease is a serious complication following stem cell and solid organ transplantation. Early recognition of the disease is important in facilitating timely therapy and improving long-term outcomes. We report a renal transplant recipient presenting with an extracran...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
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| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2017/6401086 |
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| _version_ | 1832568082640404480 |
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| author | Reuben J. Arasaratnam Alejandro Restrepo |
| author_facet | Reuben J. Arasaratnam Alejandro Restrepo |
| author_sort | Reuben J. Arasaratnam |
| collection | DOAJ |
| description | Posttransplant lymphoproliferative disease is a serious complication following stem cell and solid organ transplantation. Early recognition of the disease is important in facilitating timely therapy and improving long-term outcomes. We report a renal transplant recipient presenting with an extracranial frontoparietal soft tissue mass that was subsequently diagnosed as a B-cell lymphoma. The patient was treated successfully with immunosuppression reduction, anti-CD20 monoclonal antibody therapy, and cytotoxic chemotherapy. Our case highlights the importance of recognizing soft tissue masses in the head and neck as a potential clinical manifestation of PTLD in solid organ transplant recipients. |
| format | Article |
| id | doaj-art-6fa8d7c8f5bf4c55b0950a6ac9487eb8 |
| institution | Kabale University |
| issn | 2090-6943 2090-6951 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-6fa8d7c8f5bf4c55b0950a6ac9487eb82025-02-03T00:59:52ZengWileyCase Reports in Transplantation2090-69432090-69512017-01-01201710.1155/2017/64010866401086Posttransplant Lymphoproliferative Disease Presenting as an Extracranial MassReuben J. Arasaratnam0Alejandro Restrepo1Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USADepartment of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USAPosttransplant lymphoproliferative disease is a serious complication following stem cell and solid organ transplantation. Early recognition of the disease is important in facilitating timely therapy and improving long-term outcomes. We report a renal transplant recipient presenting with an extracranial frontoparietal soft tissue mass that was subsequently diagnosed as a B-cell lymphoma. The patient was treated successfully with immunosuppression reduction, anti-CD20 monoclonal antibody therapy, and cytotoxic chemotherapy. Our case highlights the importance of recognizing soft tissue masses in the head and neck as a potential clinical manifestation of PTLD in solid organ transplant recipients.http://dx.doi.org/10.1155/2017/6401086 |
| spellingShingle | Reuben J. Arasaratnam Alejandro Restrepo Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass Case Reports in Transplantation |
| title | Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass |
| title_full | Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass |
| title_fullStr | Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass |
| title_full_unstemmed | Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass |
| title_short | Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass |
| title_sort | posttransplant lymphoproliferative disease presenting as an extracranial mass |
| url | http://dx.doi.org/10.1155/2017/6401086 |
| work_keys_str_mv | AT reubenjarasaratnam posttransplantlymphoproliferativediseasepresentingasanextracranialmass AT alejandrorestrepo posttransplantlymphoproliferativediseasepresentingasanextracranialmass |