PRC2 promotes canalisation during endodermal differentiation.
The genetic circuitry that encodes the developmental programme of mammals is regulated by transcription factors and chromatin modifiers. During early gestation, the three embryonic germ layers are established in a process termed gastrulation. The impact of deleterious mutations in chromatin modifier...
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| Main Authors: | Jurriaan Jochem Hölzenspies, Dipta Sengupta, Wendy Anne Bickmore, Joshua Mark Brickman, Robert Scott Illingworth |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS Genetics |
| Online Access: | https://doi.org/10.1371/journal.pgen.1011584 |
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