ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE
Aim. To study the coronary atherosclerosis progression in patients with 5-year history of myocardial infarction (MI) depending on the statin therapy compliance. Material and methods. Patients (n=31) with a five year history of MI were involved into the study. Patients were divided into two groups de...
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Столичная издательская компания
2015-12-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/631 |
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| author | A. I. Chesnikova V. A. Safronenko A. V. Hripun |
| author_facet | A. I. Chesnikova V. A. Safronenko A. V. Hripun |
| author_sort | A. I. Chesnikova |
| collection | DOAJ |
| description | Aim. To study the coronary atherosclerosis progression in patients with 5-year history of myocardial infarction (MI) depending on the statin therapy compliance. Material and methods. Patients (n=31) with a five year history of MI were involved into the study. Patients were divided into two groups depending on the statin therapy compliance during 5 years after MI: group 1 — patients with high compliance, group 2 — patients with low compliance. Assessment of the coronary angiography and lipid profile was performed first time in 2005–2006 during hospital treatment for MI and after 5 years again. Results. Increase in the proportion of patients with two and three coronary vessel disease was found after 5 years of observation, despite the high rate of percutaneous coronary intervention (77.4%) and hypolipidemic therapy. Hemodynamically significant restenosis was found in 11.8% (group 1) and 21.4% (group 2) of patients. Target total cholesterol level was reached only in 42.9% and 11.8% of patients in group 1 and 2, respectively. The target level of low density cholesterol was achieved in no one patient. Conclusion. The findings suggest that in patients with 5-year history of MI coronary atherosclerosis progresses regardless of the statin therapy compliance. |
| format | Article |
| id | doaj-art-6fa191e2866a461289362fdfabbd1786 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2015-12-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-6fa191e2866a461289362fdfabbd17862025-08-23T10:00:21ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-018677277610.20996/1819-6446-2012-8-6-772-776630ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCEA. I. Chesnikova0V. A. Safronenko1A. V. Hripun2Rostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityAim. To study the coronary atherosclerosis progression in patients with 5-year history of myocardial infarction (MI) depending on the statin therapy compliance. Material and methods. Patients (n=31) with a five year history of MI were involved into the study. Patients were divided into two groups depending on the statin therapy compliance during 5 years after MI: group 1 — patients with high compliance, group 2 — patients with low compliance. Assessment of the coronary angiography and lipid profile was performed first time in 2005–2006 during hospital treatment for MI and after 5 years again. Results. Increase in the proportion of patients with two and three coronary vessel disease was found after 5 years of observation, despite the high rate of percutaneous coronary intervention (77.4%) and hypolipidemic therapy. Hemodynamically significant restenosis was found in 11.8% (group 1) and 21.4% (group 2) of patients. Target total cholesterol level was reached only in 42.9% and 11.8% of patients in group 1 and 2, respectively. The target level of low density cholesterol was achieved in no one patient. Conclusion. The findings suggest that in patients with 5-year history of MI coronary atherosclerosis progresses regardless of the statin therapy compliance.https://www.rpcardio.online/jour/article/view/631myocardial infarctioncoronary angiographystatin therapy complianceatherosclerosis progression |
| spellingShingle | A. I. Chesnikova V. A. Safronenko A. V. Hripun ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE Рациональная фармакотерапия в кардиологии myocardial infarction coronary angiography statin therapy compliance atherosclerosis progression |
| title | ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE |
| title_full | ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE |
| title_fullStr | ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE |
| title_full_unstemmed | ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE |
| title_short | ASSESSMENT OF CORONARY ATHEROSCLEROSIS PROGRESSION IN PATIENTS WITH FIVE YEAR HISTORY OF MYOCARDIAL INFARCTION DEPENDING ON THE STATIN THERAPY COMPLIANCE |
| title_sort | assessment of coronary atherosclerosis progression in patients with five year history of myocardial infarction depending on the statin therapy compliance |
| topic | myocardial infarction coronary angiography statin therapy compliance atherosclerosis progression |
| url | https://www.rpcardio.online/jour/article/view/631 |
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