Sunitinib’s Effect on Bilateral Optic Nerve Damage in Rats Following the Unilateral Clamping and Unclamping of the Common Carotid Artery

Sunitinib’s Effect on Bilateral Optic Nerve Damage in Rats Following the Unilateral Clamping and Unclamping of the Common Carotid Artery

<b>Background/objectives</b>: Common carotid artery occlusion can cause oxidant and inflammatory damage to the optic nerve. In this study, the effect of sunitinib was investigated, the antioxidant and anti-inflammatory properties of which have been previously reported and shown to be pro...

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Bibliographic Details
Main Authors: Ibrahim Cicek, Cenap Mahmut Esenulku, Ahmet Mehmet Somuncu, Seval Bulut, Nurinisa Yucel, Tugba Bal Tastan, Taha Abdulkadir Coban, Halis Suleyman
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
sunitinib
optic nerve
ischemia–reperfusion
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2227-9059/13/3/620
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