Small extracellular vesicle miRNAs as biomarkers for predicting antitumor efficacy in lung adenocarcinoma treated with chemotherapy and checkpoint blockade

Small extracellular vesicle miRNAs as biomarkers for predicting antitumor efficacy in lung adenocarcinoma treated with chemotherapy and checkpoint blockade

Checkpoint blockade combined with chemotherapy has become an important treatment option for lung cancer patients in clinical settings. However, biomarkers that effectively identify true responders remain lacking. We assessed the potential of plasma small extracellular vesicle (sEV)-derived microRNAs...

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Bibliographic Details
Main Authors: Si Sun, Fuchuang Zhang, Jiyang Zhang, Hui Yu, Zhihuang Hu, Xiaoya Xu, Xinmin Zhao, Sheng Chen, Yao Zhang, Baoning Nian, Ying Lin, Zhikuan Li, Zhenhua Wu, Bo Yu, Xianghua Wu, Huijie Wang, Xiaohua Hui, Dadong Zhang, Jialei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
sEVs
miRNA
immune checkpoint inhibitors
chemotherapy
lung cancer. sEV miRNAs predicting immunochemotherapy efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1573043/full
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