Evaluation of natural compounds as folate biosynthesis inhibitors in Mycobacterium leprae using docking, ADMET analysis, and molecular dynamics simulation
Mycobacterium leprae, the bacterium that causes leprosy, is still a public health concern which requires innovative strategies to fight drug-resistant forms. This study investigates the potential of natural compounds as FolP protein inhibitors, a key enzyme in the folate biosynthesis pathway critica...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2025-04-01
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| Series: | Open Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/chem-2025-0145 |
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