Genetic and Environmental Contributions to Serological Biomarkers of Extracellular Matrix Remodeling in Asthma: A Twin Study

Genetic and Environmental Contributions to Serological Biomarkers of Extracellular Matrix Remodeling in Asthma: A Twin Study

ABSTRACT Background Asthma is characterized by airway obstruction driven by chronic inflammation, leading to extracellular matrix (ECM) remodeling. This involves ECM alterations, including increased collagen deposition and elastolysis, resulting in airway wall thickening and irreversible airflow lim...

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Bibliographic Details
Main Authors: Matej Andelic, Vibeke Backer, Kirsten Ohm Kyvik, Signe Holm Nielsen, Simon Francis Thomsen
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Clinical and Translational Allergy
Subjects:
asthma
biomarkers
collagens
immunity
obstructions
Online Access:https://doi.org/10.1002/clt2.70089
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