Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study
Introduction: The first months after the hospitalization of cirrhotic patients are considered at high risk for new complications. Knowing the factors associated with early readmission in these individuals may contribute to the development of preventive strategies that avoid the risks and costs rela...
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| Format: | Article |
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Faculdade de Medicina do ABC
2025-02-01
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| Series: | ABCS Health Sciences |
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| Online Access: | https://nepas.emnuvens.com.br/abcshs/article/view/2339 |
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| author | Tamara Liana Zocche Cláudia Maccali Fernanda Cristina de Augustinho Elayne Cristina de Morais Rateke Camila Matiollo Ariane Borgonovo Rayes Dariana Carla Maggi Esther Buzaglo Dantas-Corrêa Leonardo de Lucca Schiavon Janaina Luz Narciso-Schiavon |
| author_facet | Tamara Liana Zocche Cláudia Maccali Fernanda Cristina de Augustinho Elayne Cristina de Morais Rateke Camila Matiollo Ariane Borgonovo Rayes Dariana Carla Maggi Esther Buzaglo Dantas-Corrêa Leonardo de Lucca Schiavon Janaina Luz Narciso-Schiavon |
| author_sort | Tamara Liana Zocche |
| collection | DOAJ |
| description |
Introduction: The first months after the hospitalization of cirrhotic patients are considered at high risk for new complications. Knowing the factors associated with early readmission in these individuals may contribute to the development of preventive strategies that avoid the risks and costs related to a new hospitalization. Objective: To investigate the factors associated with the early readmission of hospitalized patients due to acute decompensation of cirrhosis. Methods: Data from the first hospitalization of each patient was considered during the study period and were followed up to the 90th day by telephone contact. A prospective cohort study in Southern Brazil. Results: Between 2011 and 2016, 280 patients were included in the study. The mean age was 55.68±11.21 years, and 71.8% were males with a mean MELD of 15.65±5.64 and 41.4% Child-Pugh C. Early readmission occurred in 91 cases (32.5%). In the logistic regression analysis, CLIF-SOFA variables (odds ratio [OR] 1.137, 95% confidence interval [CI] 1.003–1.289, p=0.045) and several complications present in the initial hospitalization (OR 1.503, 95% CI 1.074–2.105, p=0.018) independent of early readmission. Early readmission rates were 16.8% in patients with CLIF-SOFA <8 and less than 2 complications at admission and 49.2% in those with CLIF-SOFA ≥8 and 2 or more complications at the initial hospitalization. Conclusion: Simple parameters such as CLIF-SOFA and the number of complications of cirrhosis present at hospital admission are predictors of early readmission and can be used as tools to individualize the follow-up of cirrhotic patients after hospital discharge.
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| format | Article |
| id | doaj-art-6f6ffb2ca73a432faf05be20f074b1c9 |
| institution | Kabale University |
| issn | 2318-4965 2357-8114 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Faculdade de Medicina do ABC |
| record_format | Article |
| series | ABCS Health Sciences |
| spelling | doaj-art-6f6ffb2ca73a432faf05be20f074b1c92025-02-10T05:41:11ZengFaculdade de Medicina do ABCABCS Health Sciences2318-49652357-81142025-02-0110.7322/abcshs.2023073.2339Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort studyTamara Liana Zocche0Cláudia Maccali1Fernanda Cristina de Augustinho2Elayne Cristina de Morais Rateke3Camila Matiollo4Ariane Borgonovo Rayes5Dariana Carla Maggi6Esther Buzaglo Dantas-Corrêa7Leonardo de Lucca Schiavon8Janaina Luz Narciso-Schiavon9Unidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), BrazilUnidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), BrazilUnidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), BrazilUnidade de Laboratório de Análises Clínicas, Hospital Universitário, UFSC – Florianópolis (SC) BrazilUnidade de Laboratório de Análises Clínicas, Hospital Universitário, UFSC – Florianópolis (SC) BrazilUnidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), BrazilUnidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), BrazilDepartamento de Clínica Médica, Centro de Ciências da Saúde, UFSC – Florianópolis (SC) BrazilUnidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), Brazil / Departamento de Clínica Médica, Centro de Ciências da Saúde, UFSC – Florianópolis (SC) BrazilUnidade de Gastroenterologia, Divisão do Aparelho Digestivo, Hospital Universitário, Universidade Federal de Santa Catarina (UFSC) – Florianópolis (SC), Brazil / Departamento de Clínica Médica, Centro de Ciências da Saúde, UFSC – Florianópolis (SC) Brazil Introduction: The first months after the hospitalization of cirrhotic patients are considered at high risk for new complications. Knowing the factors associated with early readmission in these individuals may contribute to the development of preventive strategies that avoid the risks and costs related to a new hospitalization. Objective: To investigate the factors associated with the early readmission of hospitalized patients due to acute decompensation of cirrhosis. Methods: Data from the first hospitalization of each patient was considered during the study period and were followed up to the 90th day by telephone contact. A prospective cohort study in Southern Brazil. Results: Between 2011 and 2016, 280 patients were included in the study. The mean age was 55.68±11.21 years, and 71.8% were males with a mean MELD of 15.65±5.64 and 41.4% Child-Pugh C. Early readmission occurred in 91 cases (32.5%). In the logistic regression analysis, CLIF-SOFA variables (odds ratio [OR] 1.137, 95% confidence interval [CI] 1.003–1.289, p=0.045) and several complications present in the initial hospitalization (OR 1.503, 95% CI 1.074–2.105, p=0.018) independent of early readmission. Early readmission rates were 16.8% in patients with CLIF-SOFA <8 and less than 2 complications at admission and 49.2% in those with CLIF-SOFA ≥8 and 2 or more complications at the initial hospitalization. Conclusion: Simple parameters such as CLIF-SOFA and the number of complications of cirrhosis present at hospital admission are predictors of early readmission and can be used as tools to individualize the follow-up of cirrhotic patients after hospital discharge. https://nepas.emnuvens.com.br/abcshs/article/view/2339liver cirrhosisopportunistic infectionsasciteshepatic encephalopathyliver function testspatient readmission |
| spellingShingle | Tamara Liana Zocche Cláudia Maccali Fernanda Cristina de Augustinho Elayne Cristina de Morais Rateke Camila Matiollo Ariane Borgonovo Rayes Dariana Carla Maggi Esther Buzaglo Dantas-Corrêa Leonardo de Lucca Schiavon Janaina Luz Narciso-Schiavon Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study ABCS Health Sciences liver cirrhosis opportunistic infections ascites hepatic encephalopathy liver function tests patient readmission |
| title | Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study |
| title_full | Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study |
| title_fullStr | Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study |
| title_full_unstemmed | Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study |
| title_short | Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study |
| title_sort | factors associated with early hospital readmission for acute decompensation of cirrhosis prospective cohort study |
| topic | liver cirrhosis opportunistic infections ascites hepatic encephalopathy liver function tests patient readmission |
| url | https://nepas.emnuvens.com.br/abcshs/article/view/2339 |
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