Application of TCM network pharmacology and experimental verification to explore the mechanism of kaempferol against epilepsy

Application of TCM network pharmacology and experimental verification to explore the mechanism of kaempferol against epilepsy

Background: Kaempferol (KF), the main active ingredient in identifying the authenticity of safflower, has a variety of pharmacological activities and neuroprotective effects. However, the mechanism of KF in the treatment of epilepsy remains unclear. This study aimed to investigate the protective eff...

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Bibliographic Details
Main Authors: Jiaojiao Zhao, Xia Qin, Lei Yang, Han Guo, Siruan Chen, Keying Tian, Qinghui Guo, Wenya Zhao, Panpan Zhang, Zhanfeng Jia, Zuxiao Yang, Dezhi Kong, Wei Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain Research Bulletin
Subjects:
Kaempferol
Epilepsy
Network pharmacology
Cell excitability
Ca2+ overload
AMPAR
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923024002843
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