A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair
(1) Background: Renal artery occlusion after F/B EVAR for abdominal aortic aneurysm is a serious complication that may require re-intervention, and understanding the hemodynamic mechanisms by which it occurs is essential to optimize the surgical procedure. (2) Methods: We used computational fluid dy...
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2025-05-01
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| author | Yuzhu Wang Yuna Sang Wendong Li Minjie Zhou Yushun Zhao Xiaodong He Chao Wang Xiaoqiang Li Zhao Liu |
| author_facet | Yuzhu Wang Yuna Sang Wendong Li Minjie Zhou Yushun Zhao Xiaodong He Chao Wang Xiaoqiang Li Zhao Liu |
| author_sort | Yuzhu Wang |
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| description | (1) Background: Renal artery occlusion after F/B EVAR for abdominal aortic aneurysm is a serious complication that may require re-intervention, and understanding the hemodynamic mechanisms by which it occurs is essential to optimize the surgical procedure. (2) Methods: We used computational fluid dynamics (CFD) to analyze the impact of various parameters on blood flow. Theoretical vascular models were constructed based on the common dimensions and angles of aortic stents and branch arteries in clinical practice. Actual case models were constructed from CT image data of six patients treated with F/B-EVAR. Data were collected for analysis after simulation and calculation by FLUENT software. (3) Results: Theoretical model simulations showed that a larger tilt angle of the branch stent, smaller branch entry depth, and larger branch stent diameter were beneficial for blood flow. In the case models, a significant difference in the tilt angle of the renal artery stents was observed between the high- and low-flow groups, while the differences in entry depth and branch stent diameter were not significant. Occluded renal arteries had lower WSS values than patent ones. (4) Conclusions: This study offers valuable guidance for optimizing stent placement in F/B EVAR to mitigate renal artery occlusion risk. |
| format | Article |
| id | doaj-art-6f58c8c28ef5420ca5ae09333ae449dd |
| institution | OA Journals |
| issn | 2306-5354 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
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| series | Bioengineering |
| spelling | doaj-art-6f58c8c28ef5420ca5ae09333ae449dd2025-08-20T02:33:43ZengMDPI AGBioengineering2306-53542025-05-0112548210.3390/bioengineering12050482A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm RepairYuzhu Wang0Yuna Sang1Wendong Li2Minjie Zhou3Yushun Zhao4Xiaodong He5Chao Wang6Xiaoqiang Li7Zhao Liu8Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, ChinaSchool of Astronautics, Harbin Institute of Technology, Harbin 150080, ChinaDepartment of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, ChinaResearch and Development Department, Nanjing Cloudure Medical Co., Ltd., Nanjing 211200, ChinaSchool of Astronautics, Harbin Institute of Technology, Harbin 150080, ChinaNational Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Harbin Institute of Technology, Harbin 150080, ChinaSchool of Astronautics, Harbin Institute of Technology, Harbin 150080, ChinaDepartment of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, ChinaDepartment of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China(1) Background: Renal artery occlusion after F/B EVAR for abdominal aortic aneurysm is a serious complication that may require re-intervention, and understanding the hemodynamic mechanisms by which it occurs is essential to optimize the surgical procedure. (2) Methods: We used computational fluid dynamics (CFD) to analyze the impact of various parameters on blood flow. Theoretical vascular models were constructed based on the common dimensions and angles of aortic stents and branch arteries in clinical practice. Actual case models were constructed from CT image data of six patients treated with F/B-EVAR. Data were collected for analysis after simulation and calculation by FLUENT software. (3) Results: Theoretical model simulations showed that a larger tilt angle of the branch stent, smaller branch entry depth, and larger branch stent diameter were beneficial for blood flow. In the case models, a significant difference in the tilt angle of the renal artery stents was observed between the high- and low-flow groups, while the differences in entry depth and branch stent diameter were not significant. Occluded renal arteries had lower WSS values than patent ones. (4) Conclusions: This study offers valuable guidance for optimizing stent placement in F/B EVAR to mitigate renal artery occlusion risk.https://www.mdpi.com/2306-5354/12/5/482F/B EVARhemodynamicsprosthetic vascular stentbranch flow |
| spellingShingle | Yuzhu Wang Yuna Sang Wendong Li Minjie Zhou Yushun Zhao Xiaodong He Chao Wang Xiaoqiang Li Zhao Liu A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair Bioengineering F/B EVAR hemodynamics prosthetic vascular stent branch flow |
| title | A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair |
| title_full | A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair |
| title_fullStr | A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair |
| title_full_unstemmed | A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair |
| title_short | A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair |
| title_sort | computational study on renal artery anatomy in patients treated with fenestrated or branched endovascular aneurysm repair |
| topic | F/B EVAR hemodynamics prosthetic vascular stent branch flow |
| url | https://www.mdpi.com/2306-5354/12/5/482 |
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