Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes

Background. Hypoglycemia due to inadequate carbohydrate intake is a frequent complication of insulin treatment of diabetic in-patients. Objective. To assess the effectiveness of a nurse-managed protocol to prevent hypoglycemia during subcutaneous insulin treatment. Design. Prospective pre-post-inter...

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Main Authors: Giuseppe Marelli, Fausto Avanzini, Giuseppe Iacuitti, Enrico Planca, Ilaria Frigerio, Giovanna Busi, Liliana Carlino, Laura Cortesi, Maria Carla Roncaglioni, Emma Riva
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2015/173956
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author Giuseppe Marelli
Fausto Avanzini
Giuseppe Iacuitti
Enrico Planca
Ilaria Frigerio
Giovanna Busi
Liliana Carlino
Laura Cortesi
Maria Carla Roncaglioni
Emma Riva
author_facet Giuseppe Marelli
Fausto Avanzini
Giuseppe Iacuitti
Enrico Planca
Ilaria Frigerio
Giovanna Busi
Liliana Carlino
Laura Cortesi
Maria Carla Roncaglioni
Emma Riva
author_sort Giuseppe Marelli
collection DOAJ
description Background. Hypoglycemia due to inadequate carbohydrate intake is a frequent complication of insulin treatment of diabetic in-patients. Objective. To assess the effectiveness of a nurse-managed protocol to prevent hypoglycemia during subcutaneous insulin treatment. Design. Prospective pre-post-intervention study. Methods. In 350 consecutive diabetic in-patients the incidence of hypoglycemia (blood glucose < 70 mg/dL) during subcutaneous insulin treatment was assessed before (phase A) and after (phase B) the protocol was adopted to permit (1) the patient to opt for substitutive food to integrate incomplete carbohydrate intake in the meal; (2) in case of lack of appetite or repeatedly partial intake of the planned food, prandial insulin administered at the end of the meal to be related to the actual amount of carbohydrates eaten; (3) intravenous infusion of glucose during prolonged fasting. Results. Eighty-four patients in phase A and 266 in phase B received subcutaneous insulin for median periods of, respectively, 7 (Q1–Q3 6–12) and 6 days (Q1–Q3 4–9). Hypoglycemic events declined significantly from 0.34 ± 0.33 per day in phase A to 0.19 ± 0.30 in phase B (P>0.001). Conclusions. A nurse-managed protocol focusing on carbohydrate intake reduced the incidence of hypoglycemia in patients with diabetes receiving subcutaneous insulin in hospital.
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spelling doaj-art-6f3c969ca30e4691b1711a3f84916eca2025-02-03T01:27:12ZengWileyJournal of Diabetes Research2314-67452314-67532015-01-01201510.1155/2015/173956173956Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with DiabetesGiuseppe Marelli0Fausto Avanzini1Giuseppe Iacuitti2Enrico Planca3Ilaria Frigerio4Giovanna Busi5Liliana Carlino6Laura Cortesi7Maria Carla Roncaglioni8Emma Riva9Diabetes and Metabolic Diseases Unit, Ospedale di Desio, Desio, ItalyDivision of Cardiology and Intensive Cardiac Care Unit, Ospedale di Desio, Desio, ItalyDivision of Cardiology and Intensive Cardiac Care Unit, Ospedale di Desio, Desio, ItalyDivision of Cardiology and Intensive Cardiac Care Unit, Ospedale di Desio, Desio, ItalyDivision of Cardiology and Intensive Cardiac Care Unit, Ospedale di Desio, Desio, ItalyDivision of Cardiology and Intensive Cardiac Care Unit, Ospedale di Desio, Desio, ItalyDivision of Cardiology and Intensive Cardiac Care Unit, Ospedale di Desio, Desio, ItalyIRCCS-Istituto di Ricerche Farmacologiche “Mario Negri”, Via Giuseppe La Masa 19, 20156 Milan, ItalyIRCCS-Istituto di Ricerche Farmacologiche “Mario Negri”, Via Giuseppe La Masa 19, 20156 Milan, ItalyIRCCS-Istituto di Ricerche Farmacologiche “Mario Negri”, Via Giuseppe La Masa 19, 20156 Milan, ItalyBackground. Hypoglycemia due to inadequate carbohydrate intake is a frequent complication of insulin treatment of diabetic in-patients. Objective. To assess the effectiveness of a nurse-managed protocol to prevent hypoglycemia during subcutaneous insulin treatment. Design. Prospective pre-post-intervention study. Methods. In 350 consecutive diabetic in-patients the incidence of hypoglycemia (blood glucose < 70 mg/dL) during subcutaneous insulin treatment was assessed before (phase A) and after (phase B) the protocol was adopted to permit (1) the patient to opt for substitutive food to integrate incomplete carbohydrate intake in the meal; (2) in case of lack of appetite or repeatedly partial intake of the planned food, prandial insulin administered at the end of the meal to be related to the actual amount of carbohydrates eaten; (3) intravenous infusion of glucose during prolonged fasting. Results. Eighty-four patients in phase A and 266 in phase B received subcutaneous insulin for median periods of, respectively, 7 (Q1–Q3 6–12) and 6 days (Q1–Q3 4–9). Hypoglycemic events declined significantly from 0.34 ± 0.33 per day in phase A to 0.19 ± 0.30 in phase B (P>0.001). Conclusions. A nurse-managed protocol focusing on carbohydrate intake reduced the incidence of hypoglycemia in patients with diabetes receiving subcutaneous insulin in hospital.http://dx.doi.org/10.1155/2015/173956
spellingShingle Giuseppe Marelli
Fausto Avanzini
Giuseppe Iacuitti
Enrico Planca
Ilaria Frigerio
Giovanna Busi
Liliana Carlino
Laura Cortesi
Maria Carla Roncaglioni
Emma Riva
Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes
Journal of Diabetes Research
title Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes
title_full Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes
title_fullStr Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes
title_full_unstemmed Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes
title_short Effectiveness of a Nurse-Managed Protocol to Prevent Hypoglycemia in Hospitalized Patients with Diabetes
title_sort effectiveness of a nurse managed protocol to prevent hypoglycemia in hospitalized patients with diabetes
url http://dx.doi.org/10.1155/2015/173956
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