In space fabrication of Janus base nano matrix for improved assembly and bioactivity
Abstract Nanomaterials have a broad impact on both space and biomedical research but have never been produced in-space for regenerative applications. During the Axiom-2 (Ax-2) mission, our team completed the first-ever low Earth orbit (LEO) manufacturing of Janus base nanomaterials (JBNs) for cartil...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-07-01
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| Series: | npj Microgravity |
| Online Access: | https://doi.org/10.1038/s41526-025-00482-z |
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| _version_ | 1849402070570893312 |
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| author | Anne Yau Maxwell Landolina Mari Anne Snow Pinar Mesci Brandon Williams James B. Hoying Jana Stoudemire Rayyanah Barnawi Peggy Whitson Rose Hernandez Derek Duflo Honglu Wu Yupeng Chen |
| author_facet | Anne Yau Maxwell Landolina Mari Anne Snow Pinar Mesci Brandon Williams James B. Hoying Jana Stoudemire Rayyanah Barnawi Peggy Whitson Rose Hernandez Derek Duflo Honglu Wu Yupeng Chen |
| author_sort | Anne Yau |
| collection | DOAJ |
| description | Abstract Nanomaterials have a broad impact on both space and biomedical research but have never been produced in-space for regenerative applications. During the Axiom-2 (Ax-2) mission, our team completed the first-ever low Earth orbit (LEO) manufacturing of Janus base nanomaterials (JBNs) for cartilage tissue regeneration. This fabrication of JBNs in LEO resulted in superior product homogeneity, stability, and loading ability compared to Earth samples, demonstrating the benefits of manufacturing in microgravity. |
| format | Article |
| id | doaj-art-6f093d7ddb06486eb7450136a80a97ea |
| institution | Kabale University |
| issn | 2373-8065 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Microgravity |
| spelling | doaj-art-6f093d7ddb06486eb7450136a80a97ea2025-08-20T03:37:38ZengNature Portfolionpj Microgravity2373-80652025-07-011111610.1038/s41526-025-00482-zIn space fabrication of Janus base nano matrix for improved assembly and bioactivityAnne Yau0Maxwell Landolina1Mari Anne Snow2Pinar Mesci3Brandon Williams4James B. Hoying5Jana Stoudemire6Rayyanah Barnawi7Peggy Whitson8Rose Hernandez9Derek Duflo10Honglu Wu11Yupeng Chen12Department of Biomedical Engineering, University of ConnecticutDepartment of Biomedical Engineering, University of ConnecticutEascra Biotech IncAxiom SpaceAxiom SpaceAdvanced Solution Life SciencesAxiom SpaceSaudi Space AgencyAxiom SpaceISS National Laboratory ® (ISS National Lab)ISS National Laboratory ® (ISS National Lab)National Aeronautics and Space Administration (NASA)Department of Biomedical Engineering, University of ConnecticutAbstract Nanomaterials have a broad impact on both space and biomedical research but have never been produced in-space for regenerative applications. During the Axiom-2 (Ax-2) mission, our team completed the first-ever low Earth orbit (LEO) manufacturing of Janus base nanomaterials (JBNs) for cartilage tissue regeneration. This fabrication of JBNs in LEO resulted in superior product homogeneity, stability, and loading ability compared to Earth samples, demonstrating the benefits of manufacturing in microgravity.https://doi.org/10.1038/s41526-025-00482-z |
| spellingShingle | Anne Yau Maxwell Landolina Mari Anne Snow Pinar Mesci Brandon Williams James B. Hoying Jana Stoudemire Rayyanah Barnawi Peggy Whitson Rose Hernandez Derek Duflo Honglu Wu Yupeng Chen In space fabrication of Janus base nano matrix for improved assembly and bioactivity npj Microgravity |
| title | In space fabrication of Janus base nano matrix for improved assembly and bioactivity |
| title_full | In space fabrication of Janus base nano matrix for improved assembly and bioactivity |
| title_fullStr | In space fabrication of Janus base nano matrix for improved assembly and bioactivity |
| title_full_unstemmed | In space fabrication of Janus base nano matrix for improved assembly and bioactivity |
| title_short | In space fabrication of Janus base nano matrix for improved assembly and bioactivity |
| title_sort | in space fabrication of janus base nano matrix for improved assembly and bioactivity |
| url | https://doi.org/10.1038/s41526-025-00482-z |
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