Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue

Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue

Objective: Sex differences in adipose tissue impact metabolic health, but the underlying molecular mechanisms remain unclear. We previously identified a female-specific chr17 trans-eQTL hotspot regulating mitochondrial gene expression in gonadal white adipose tissue (gWAT). Here, we tested whether i...

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Bibliographic Details
Main Authors: Dorota Kaminska, Calvin Pan, Laurent Vergnes, Ashlyn Ro, Gurugowtham Ulaganathan, Aldons J. Lusis
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Molecular Metabolism
Subjects:
iWAT
gWAT
Mitochondria
Metabolism
Sex
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825001346
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