CBX4 regulation of senescence and associated diseases: Molecular pathways and mechanisms

Polycomb repressive complex 1 (PRC1) is a multisubunit, evolutionarily conserved epigenetic regulator critical to numerous biological processes. Being a core component of the canonical PRC1 subunit within the Polycomb group protein complex, Chromobox4 (CBX4), a SUMO E3 ligase, can bind to H3K27me3 a...

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Bibliographic Details
Main Authors: Qianxing Hu, Linming Su, Wanli Zhao, Yinuo Jin, Liang Jin, Yue Yang, Fangfang Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Pharmacological Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825001306
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