Pouchitis After Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) are becoming increasingly used for various cancers, but their association with immune-related adverse events often leads to significant morbidity and mortality. Here we report 2 unusual cases of pouchitis after ICI therapy—treated with steroids and biologics. To o...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2023-08-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0414 |
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| Summary: | Immune checkpoint inhibitors (ICIs) are becoming increasingly used for various cancers, but their association with immune-related adverse events often leads to significant morbidity and mortality. Here we report 2 unusual cases of pouchitis after ICI therapy—treated with steroids and biologics. To our knowledge, this is the first example to be reported in literature. One patient achieved short-term remission, while the other achieved long-term remission without further flares. |
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| ISSN: | 2767-7664 |