4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain
Purpose: To investigate the pathological changes of the synovium in mice with post-traumatic osteoarthritis (PTOA) treated with 4-octyl itaconate (4-OI) and evaluate the therapeutic effects of 4-OI. Methods: In the phenotypic validation experiment, the mice were randomly divided into 3 groups: wild-...
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Main Authors: | Yu-Zhen Tang, Wan Chen, Bao-Yun Xu, Gang He, Xiu-Cheng Fan, Kang-Lai Tang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Chinese Journal of Traumatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1008127524001548 |
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