Necrotizing Sarcoid Granulomatosis with Pneumothorax
Necrotizing sarcoid granulomatosis (NSG) is a rare granulomatous pneumonitis which is composed of a background of sarcoidosis-like granulomas, granulomatous vasculitis, and variable amount of necrosis. We reported a case of a 38-year-old nonsmoking woman presented with left-sided chest pain and dysp...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/4648720 |
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| author | Mihan Pourabdollah Seyed Reza Saghebi Mitra Abdolahi Mitra Sadat Rezaei |
| author_facet | Mihan Pourabdollah Seyed Reza Saghebi Mitra Abdolahi Mitra Sadat Rezaei |
| author_sort | Mihan Pourabdollah |
| collection | DOAJ |
| description | Necrotizing sarcoid granulomatosis (NSG) is a rare granulomatous pneumonitis which is composed of a background of sarcoidosis-like granulomas, granulomatous vasculitis, and variable amount of necrosis. We reported a case of a 38-year-old nonsmoking woman presented with left-sided chest pain and dyspnea for three days. Chest CT scan exhibited collapse consolidation of the left lower lobe with the presence of two separated small-sized cystic lesions within the collapsed segment. Lung lesion resection was performed, and histological examination confirmed the diagnosis by excluding other causes of granulomatous diseases. The prognosis of NSG is favorable, and medical treatment is usually not necessary, as well as in our case. NSG is a rare disease with nonspecific symptoms and good prognosis which is frequently confused with Wegener’s granulomatosis, sarcoidosis, and Churg–Strauss syndrome. This entity should also be considered as differential diagnosis of necrotizing granulomatous diseases. |
| format | Article |
| id | doaj-art-6ef6b62f003e43aba14760235b8d2e0e |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-6ef6b62f003e43aba14760235b8d2e0e2025-08-20T03:34:08ZengWileyCase Reports in Medicine1687-96271687-96352019-01-01201910.1155/2019/46487204648720Necrotizing Sarcoid Granulomatosis with PneumothoraxMihan Pourabdollah0Seyed Reza Saghebi1Mitra Abdolahi2Mitra Sadat Rezaei3Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IranThoracic Surgery Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Pathology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Pathology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranNecrotizing sarcoid granulomatosis (NSG) is a rare granulomatous pneumonitis which is composed of a background of sarcoidosis-like granulomas, granulomatous vasculitis, and variable amount of necrosis. We reported a case of a 38-year-old nonsmoking woman presented with left-sided chest pain and dyspnea for three days. Chest CT scan exhibited collapse consolidation of the left lower lobe with the presence of two separated small-sized cystic lesions within the collapsed segment. Lung lesion resection was performed, and histological examination confirmed the diagnosis by excluding other causes of granulomatous diseases. The prognosis of NSG is favorable, and medical treatment is usually not necessary, as well as in our case. NSG is a rare disease with nonspecific symptoms and good prognosis which is frequently confused with Wegener’s granulomatosis, sarcoidosis, and Churg–Strauss syndrome. This entity should also be considered as differential diagnosis of necrotizing granulomatous diseases.http://dx.doi.org/10.1155/2019/4648720 |
| spellingShingle | Mihan Pourabdollah Seyed Reza Saghebi Mitra Abdolahi Mitra Sadat Rezaei Necrotizing Sarcoid Granulomatosis with Pneumothorax Case Reports in Medicine |
| title | Necrotizing Sarcoid Granulomatosis with Pneumothorax |
| title_full | Necrotizing Sarcoid Granulomatosis with Pneumothorax |
| title_fullStr | Necrotizing Sarcoid Granulomatosis with Pneumothorax |
| title_full_unstemmed | Necrotizing Sarcoid Granulomatosis with Pneumothorax |
| title_short | Necrotizing Sarcoid Granulomatosis with Pneumothorax |
| title_sort | necrotizing sarcoid granulomatosis with pneumothorax |
| url | http://dx.doi.org/10.1155/2019/4648720 |
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