The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks

Background: The present study investigated the association between fetal renal artery Doppler flow, hourly urine output, and amniotic fluid volume in fetuses with a gestational age of 30 to 34 weeks in normal pregnancies. Methods: This cross-sectional study was conducted on 95 eligible pregnant wome...

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Main Authors: Neda Nikpour, Maryam Nurzadeh, Narjes Tavakolikia, Lida Mohammadpour, Mahsa Naemi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2024-10-01
Series:Iranian Journal of Neonatology
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Online Access:https://ijn.mums.ac.ir/article_24653_d514a321381bccf9edea2a004f9039aa.pdf
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author Neda Nikpour
Maryam Nurzadeh
Narjes Tavakolikia
Lida Mohammadpour
Mahsa Naemi
author_facet Neda Nikpour
Maryam Nurzadeh
Narjes Tavakolikia
Lida Mohammadpour
Mahsa Naemi
author_sort Neda Nikpour
collection DOAJ
description Background: The present study investigated the association between fetal renal artery Doppler flow, hourly urine output, and amniotic fluid volume in fetuses with a gestational age of 30 to 34 weeks in normal pregnancies. Methods: This cross-sectional study was conducted on 95 eligible pregnant women referred for their routine third-trimester care from March 2022 to March 2023. Each fetus's amniotic fluid volume, kidney size, and hourly urine output were recorded in resistance (RI) and plausibility (PI) indexes of the umbilical and renal arteries. The hourly urine production was calculated by considering bladder volume differences at a 30-minute duration. Results: With gestational age increasing, amniotic fluid volume (p-value=0.005) and the hourly urine output (p-value=0.005) increased significantly. RI of umbilical (p-value=0.022), right (p-value<0.001), and left (p-value=0.001) renal arteries and PI of right (p-value=0.042) and left (p-value=0.001) renal arteries decreased significantly through the pregnancy. There was a negative linear association between RI and PI of the renal arteries with hourly urine output. The results showed that the mean of renal artery Doppler indices, including right and left RI (0.87 ± 0.08 vs. 0.88 ± 0.07, p-value=0.274) and right and left PI (2.52 ± 0.59 vs. 2.56 ± 0.64, p-value=0.614) was similar in both sides. In adjusted linear regression analysis, two variables of gestational age and renal artery RI were (p-value<0.001) significantly associated with hourly urine output. Conclusion: The fetus's renal artery Doppler findings and urine outputs seem to represent fetal renal function, warning the physicians about post-natal evaluation after birth.
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spelling doaj-art-6ef64b662c834866acafeb31f88187e72025-08-20T03:56:05ZengMashhad University of Medical SciencesIranian Journal of Neonatology2251-75102322-21582024-10-01154495310.22038/ijn.2024.79239.253524653The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 WeeksNeda Nikpour0Maryam Nurzadeh1Narjes Tavakolikia2Lida Mohammadpour3Mahsa Naemi4Department of Obstetrics and Gynecology, Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, IranDepartment of Fetomaternal, Faculty of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranMedicine Specialist in Preventive and Social Medicine, Head of family health in department of health. Tehran University of Medical Sciences, Tehran, IranDepartment of Fetomaternal, Faculty of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Fetomaternal, Faculty of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranBackground: The present study investigated the association between fetal renal artery Doppler flow, hourly urine output, and amniotic fluid volume in fetuses with a gestational age of 30 to 34 weeks in normal pregnancies. Methods: This cross-sectional study was conducted on 95 eligible pregnant women referred for their routine third-trimester care from March 2022 to March 2023. Each fetus's amniotic fluid volume, kidney size, and hourly urine output were recorded in resistance (RI) and plausibility (PI) indexes of the umbilical and renal arteries. The hourly urine production was calculated by considering bladder volume differences at a 30-minute duration. Results: With gestational age increasing, amniotic fluid volume (p-value=0.005) and the hourly urine output (p-value=0.005) increased significantly. RI of umbilical (p-value=0.022), right (p-value<0.001), and left (p-value=0.001) renal arteries and PI of right (p-value=0.042) and left (p-value=0.001) renal arteries decreased significantly through the pregnancy. There was a negative linear association between RI and PI of the renal arteries with hourly urine output. The results showed that the mean of renal artery Doppler indices, including right and left RI (0.87 ± 0.08 vs. 0.88 ± 0.07, p-value=0.274) and right and left PI (2.52 ± 0.59 vs. 2.56 ± 0.64, p-value=0.614) was similar in both sides. In adjusted linear regression analysis, two variables of gestational age and renal artery RI were (p-value<0.001) significantly associated with hourly urine output. Conclusion: The fetus's renal artery Doppler findings and urine outputs seem to represent fetal renal function, warning the physicians about post-natal evaluation after birth.https://ijn.mums.ac.ir/article_24653_d514a321381bccf9edea2a004f9039aa.pdfdopplerumbilical arteriesultrasonography
spellingShingle Neda Nikpour
Maryam Nurzadeh
Narjes Tavakolikia
Lida Mohammadpour
Mahsa Naemi
The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks
Iranian Journal of Neonatology
doppler
umbilical arteries
ultrasonography
title The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks
title_full The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks
title_fullStr The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks
title_full_unstemmed The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks
title_short The Association between Fetal Renal Artery Doppler Flow with Hourly Urine Output and Amniotic Fluid Volume of Fetuses with a Gestational Age of 30 to 34 Weeks
title_sort association between fetal renal artery doppler flow with hourly urine output and amniotic fluid volume of fetuses with a gestational age of 30 to 34 weeks
topic doppler
umbilical arteries
ultrasonography
url https://ijn.mums.ac.ir/article_24653_d514a321381bccf9edea2a004f9039aa.pdf
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