Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis

Abstract Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Methods This work was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Fu...

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Main Authors: Ahmed Ahmed, Tarek A. Abdel Aziz, Mohannad M. R. AlAsaad, Motaz Majthoob, Kamaleldin Ahmed Altahmody
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-024-03269-7
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author Ahmed Ahmed
Tarek A. Abdel Aziz
Mohannad M. R. AlAsaad
Motaz Majthoob
Kamaleldin Ahmed Altahmody
author_facet Ahmed Ahmed
Tarek A. Abdel Aziz
Mohannad M. R. AlAsaad
Motaz Majthoob
Kamaleldin Ahmed Altahmody
author_sort Ahmed Ahmed
collection DOAJ
description Abstract Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Methods This work was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Full text research articles discussing clinical or cost-effectiveness aspects of Inspiris Resilia bioprosthesis published in English were included in this analysis. Studies were excluded if they weren’t exclusively conducted on patients submitted to surgical aortic valve replacement using the Inspiris Resilia bioprosthesis. Results The technical success rate was almost perfect in all studies. Reported complications included severe prosthesis-patient mismatch, reoperation, endocarditis, and paravalvular leak. In almost all studies, there were significant improvement of NYHA at the end of follow up as compared to baseline. In all studies, there were significant improvement of one or more hemodynamic parameters at the end of follow up as compared to baseline. Conclusions Surgical aortic valve replacement using Inspiris Resilia tissue valve appears to be safe and effective with low rate of aortic valve and systemic complications and mortality. Its performance appears to be equal to or better than many other bioprosthetic valves. As compared to mechanical valves, its use is suggested to be more cost-effective.
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institution Kabale University
issn 1749-8090
language English
publishDate 2025-02-01
publisher BMC
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series Journal of Cardiothoracic Surgery
spelling doaj-art-6ed8a583dd3941628407822d4e37e1802025-02-09T12:53:52ZengBMCJournal of Cardiothoracic Surgery1749-80902025-02-0120111410.1186/s13019-024-03269-7Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesisAhmed Ahmed0Tarek A. Abdel Aziz1Mohannad M. R. AlAsaad2Motaz Majthoob3Kamaleldin Ahmed Altahmody4Cardiothoracic Surgery Department, Ain Shams UniversityDubai HospitalDubai HospitalDubai HospitalDubai HospitalAbstract Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Methods This work was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Full text research articles discussing clinical or cost-effectiveness aspects of Inspiris Resilia bioprosthesis published in English were included in this analysis. Studies were excluded if they weren’t exclusively conducted on patients submitted to surgical aortic valve replacement using the Inspiris Resilia bioprosthesis. Results The technical success rate was almost perfect in all studies. Reported complications included severe prosthesis-patient mismatch, reoperation, endocarditis, and paravalvular leak. In almost all studies, there were significant improvement of NYHA at the end of follow up as compared to baseline. In all studies, there were significant improvement of one or more hemodynamic parameters at the end of follow up as compared to baseline. Conclusions Surgical aortic valve replacement using Inspiris Resilia tissue valve appears to be safe and effective with low rate of aortic valve and systemic complications and mortality. Its performance appears to be equal to or better than many other bioprosthetic valves. As compared to mechanical valves, its use is suggested to be more cost-effective.https://doi.org/10.1186/s13019-024-03269-7Aortic valveAortic valve replacementBioprosthesisInspiris Resilia valve
spellingShingle Ahmed Ahmed
Tarek A. Abdel Aziz
Mohannad M. R. AlAsaad
Motaz Majthoob
Kamaleldin Ahmed Altahmody
Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
Journal of Cardiothoracic Surgery
Aortic valve
Aortic valve replacement
Bioprosthesis
Inspiris Resilia valve
title Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
title_full Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
title_fullStr Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
title_full_unstemmed Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
title_short Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis
title_sort early and late clinical outcomes and cost effectiveness of aortic valve replacement using the inspiris resilia bioprosthesis
topic Aortic valve
Aortic valve replacement
Bioprosthesis
Inspiris Resilia valve
url https://doi.org/10.1186/s13019-024-03269-7
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AT mohannadmralasaad earlyandlateclinicaloutcomesandcosteffectivenessofaorticvalvereplacementusingtheinspirisresiliabioprosthesis
AT motazmajthoob earlyandlateclinicaloutcomesandcosteffectivenessofaorticvalvereplacementusingtheinspirisresiliabioprosthesis
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