Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review
Intrahepatic cholestasis of pregnancy (ICP) is a condition that usually affects the 3rd trimester-pregnant women and is associated with adverse pregnancy outcomes. We present a 31-year-old G2P1 patient with symptoms of ICP as early as 10 weeks of gestation (WG). Her pruritis was initially attributed...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2019/4980610 |
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| author | Anastasia A. Salame Mohammad J. Jaffal Marco A. Mouanness Amal R. Nasser Eddin Labib M. Ghulmiyyah |
| author_facet | Anastasia A. Salame Mohammad J. Jaffal Marco A. Mouanness Amal R. Nasser Eddin Labib M. Ghulmiyyah |
| author_sort | Anastasia A. Salame |
| collection | DOAJ |
| description | Intrahepatic cholestasis of pregnancy (ICP) is a condition that usually affects the 3rd trimester-pregnant women and is associated with adverse pregnancy outcomes. We present a 31-year-old G2P1 patient with symptoms of ICP as early as 10 weeks of gestation (WG). Her pruritis was initially attributed to eczema. Due to the intensity of her discomfort and failure of topical treatment, ICP was suspected, total bile acid salt levels were taken and ursodeoxycholic acid was subsequently started at 18 WG. The patient was followed closely during her pregnancy to adjust the dose of the medication accordingly. Induction of labor was performed at 37 WG without complications. This case demonstrated the importance of clinical suspicion in the setting of such symptomatology in order not to miss or delay treatment of threatening conditions such as ICP. |
| format | Article |
| id | doaj-art-6ec28a8f08524bb4b08f6708c5b2b137 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-6ec28a8f08524bb4b08f6708c5b2b1372025-02-03T01:20:28ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922019-01-01201910.1155/2019/49806104980610Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature ReviewAnastasia A. Salame0Mohammad J. Jaffal1Marco A. Mouanness2Amal R. Nasser Eddin3Labib M. Ghulmiyyah4American University of Beirut Medical Center, Beirut PO Box: 11-0236, LebanonAmerican University of Beirut Medical Center, Beirut PO Box: 11-0236, LebanonAmerican University of Beirut Medical Center, Beirut PO Box: 11-0236, LebanonAmerican University of Beirut Medical Center, Beirut PO Box: 11-0236, LebanonAmerican University of Beirut Medical Center, Beirut PO Box: 11-0236, LebanonIntrahepatic cholestasis of pregnancy (ICP) is a condition that usually affects the 3rd trimester-pregnant women and is associated with adverse pregnancy outcomes. We present a 31-year-old G2P1 patient with symptoms of ICP as early as 10 weeks of gestation (WG). Her pruritis was initially attributed to eczema. Due to the intensity of her discomfort and failure of topical treatment, ICP was suspected, total bile acid salt levels were taken and ursodeoxycholic acid was subsequently started at 18 WG. The patient was followed closely during her pregnancy to adjust the dose of the medication accordingly. Induction of labor was performed at 37 WG without complications. This case demonstrated the importance of clinical suspicion in the setting of such symptomatology in order not to miss or delay treatment of threatening conditions such as ICP.http://dx.doi.org/10.1155/2019/4980610 |
| spellingShingle | Anastasia A. Salame Mohammad J. Jaffal Marco A. Mouanness Amal R. Nasser Eddin Labib M. Ghulmiyyah Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review Case Reports in Obstetrics and Gynecology |
| title | Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review |
| title_full | Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review |
| title_fullStr | Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review |
| title_full_unstemmed | Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review |
| title_short | Unexplained First Trimester Intrahepatic Cholestasis of Pregnancy: A Case Report and Literature Review |
| title_sort | unexplained first trimester intrahepatic cholestasis of pregnancy a case report and literature review |
| url | http://dx.doi.org/10.1155/2019/4980610 |
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