Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada

Background and Aim. Obesity (BMI ≥ 30 kg/m2) is associated with advanced cardiovascular disease requiring procedures such as percutaneous coronary intervention (PCI). Studies report better outcomes in obese patients having these procedures but results are conflicting or inconsistent. Newfoundland an...

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Main Authors: Anne B. Gregory, Kendra K. Lester, Deborah M. Gregory, Laurie K. Twells, William K. Midodzi, Neil J. Pearce
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/7154267
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author Anne B. Gregory
Kendra K. Lester
Deborah M. Gregory
Laurie K. Twells
William K. Midodzi
Neil J. Pearce
author_facet Anne B. Gregory
Kendra K. Lester
Deborah M. Gregory
Laurie K. Twells
William K. Midodzi
Neil J. Pearce
author_sort Anne B. Gregory
collection DOAJ
description Background and Aim. Obesity (BMI ≥ 30 kg/m2) is associated with advanced cardiovascular disease requiring procedures such as percutaneous coronary intervention (PCI). Studies report better outcomes in obese patients having these procedures but results are conflicting or inconsistent. Newfoundland and Labrador (NL) has the highest rate of obesity in Canada. The aim of the study was to examine the relationship between BMI and vascular and nonvascular complications in patients undergoing PCI in NL. Methods. We studied 6473 patients identified in the APPROACH-NL database who underwent PCI from May 2006 to December 2013. BMI categories included normal, 18.5 ≤ BMI < 25.0 (n=1073); overweight, 25.0 ≤ BMI < 30 (n=2608); and obese, BMI ≥ 30.0 (n=2792). Results. Patients with obesity were younger and had a higher incidence of diabetes, hypertension, and family history of cardiac disease. Obese patients experienced less vascular complications (normal, overweight, and obese: 8.2%, 7.2%, and 5.3%, p=0.001). No significant differences were observed for in-lab (4.0%, 3.3%, and 3.1%, p=0.386) or postprocedural (1.0%, 0.8%, and 0.9%, p=0.725) nonvascular complications. After adjusting for covariates, BMI was not a significant factor associated with adverse outcomes. Conclusion. Overweight and obesity were not independent correlates of short-term vascular and nonvascular complications among patients undergoing PCI.
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spelling doaj-art-6eb75436a1394f8dbf1fb30314176f692025-02-03T01:28:49ZengWileyCardiology Research and Practice2090-80162090-05972016-01-01201610.1155/2016/71542677154267Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, CanadaAnne B. Gregory0Kendra K. Lester1Deborah M. Gregory2Laurie K. Twells3William K. Midodzi4Neil J. Pearce5Eastern Health, St. John’s, NL, A1B 3V6, CanadaDepartment of Clinical Epidemiology, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1B 3V6, CanadaDepartment of Clinical Epidemiology, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1B 3V6, CanadaDepartment of Clinical Epidemiology, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1B 3V6, CanadaDepartment of Clinical Epidemiology, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1B 3V6, CanadaEastern Health, St. John’s, NL, A1B 3V6, CanadaBackground and Aim. Obesity (BMI ≥ 30 kg/m2) is associated with advanced cardiovascular disease requiring procedures such as percutaneous coronary intervention (PCI). Studies report better outcomes in obese patients having these procedures but results are conflicting or inconsistent. Newfoundland and Labrador (NL) has the highest rate of obesity in Canada. The aim of the study was to examine the relationship between BMI and vascular and nonvascular complications in patients undergoing PCI in NL. Methods. We studied 6473 patients identified in the APPROACH-NL database who underwent PCI from May 2006 to December 2013. BMI categories included normal, 18.5 ≤ BMI < 25.0 (n=1073); overweight, 25.0 ≤ BMI < 30 (n=2608); and obese, BMI ≥ 30.0 (n=2792). Results. Patients with obesity were younger and had a higher incidence of diabetes, hypertension, and family history of cardiac disease. Obese patients experienced less vascular complications (normal, overweight, and obese: 8.2%, 7.2%, and 5.3%, p=0.001). No significant differences were observed for in-lab (4.0%, 3.3%, and 3.1%, p=0.386) or postprocedural (1.0%, 0.8%, and 0.9%, p=0.725) nonvascular complications. After adjusting for covariates, BMI was not a significant factor associated with adverse outcomes. Conclusion. Overweight and obesity were not independent correlates of short-term vascular and nonvascular complications among patients undergoing PCI.http://dx.doi.org/10.1155/2016/7154267
spellingShingle Anne B. Gregory
Kendra K. Lester
Deborah M. Gregory
Laurie K. Twells
William K. Midodzi
Neil J. Pearce
Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada
Cardiology Research and Practice
title Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada
title_full Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada
title_fullStr Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada
title_full_unstemmed Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada
title_short Impact of Body Mass Index on Short-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention in Newfoundland and Labrador, Canada
title_sort impact of body mass index on short term outcomes in patients undergoing percutaneous coronary intervention in newfoundland and labrador canada
url http://dx.doi.org/10.1155/2016/7154267
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