Multi-omics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cells

Abstract Brain tumours disproportionately affect children and are the largest cause of paediatric cancer-related death. Novel therapies that engage the immune system, such as oncolytic viruses (OVs), hold great promise and are desperately needed. Zika virus (ZIKV) infects and destroys aggressive cel...

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Bibliographic Details
Main Authors: Matthew Sherwood, Thiago G. Mitsugi, Carolini Kaid, Brandon Coke, Mayana Zatz, Kevin Maringer, Oswaldo K. Okamoto, Rob M. Ewing
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97804-8
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