Predicting high confidence ctDNA somatic variants with ensemble machine learning models
Abstract Circulating tumour DNA (ctDNA) is a minimally invasive cancer biomarker that can be used to inform treatment of cancer patients. The utility of ctDNA as a cancer biomarker depends on the ability to accurately detect somatic variants associated with cancer. Accurate somatic variant detection...
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| Main Authors: | Rugare Maruzani, Liam Brierley, Andrea Jorgensen, Anna Fowler |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-01326-2 |
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