New mechanism of LncRNA: In addition to act as a ceRNA
Long non-coding RNAs (LncRNAs) are a class of RNA molecules with nucleic acid lengths ranging from 200 bp to 100 kb that cannot code for proteins, which are diverse and widely expressed in both animals and plants. Scholars have found that lncRNAs can regulate human physiological processes at the gen...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2024-12-01
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| Series: | Non-coding RNA Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S246805402400101X |
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| author | Jiahao Zhang Huike Zhu Linjing Li Yuting Gao Boyi Yu Guorong Ma Xiaodong Jin Yingbiao Sun |
| author_facet | Jiahao Zhang Huike Zhu Linjing Li Yuting Gao Boyi Yu Guorong Ma Xiaodong Jin Yingbiao Sun |
| author_sort | Jiahao Zhang |
| collection | DOAJ |
| description | Long non-coding RNAs (LncRNAs) are a class of RNA molecules with nucleic acid lengths ranging from 200 bp to 100 kb that cannot code for proteins, which are diverse and widely expressed in both animals and plants. Scholars have found that lncRNAs can regulate human physiological processes at the gene and protein levels, mainly through the regulation of epigenetic, transcriptional and post-transcriptional levels of genes and proteins, as well as in the immune response by regulating the expression of immune cells and inflammatory factors, and thus participate in the occurrence and development of a variety of diseases. From the downstream targets of lncRNAs, we summarize the new research progress of lncRNA mechanisms other than miRNA sponges in recent years, aiming to provide new ideas and directions for the study of lncRNA mechanisms. |
| format | Article |
| id | doaj-art-6e9c9e6340c64188bda0fbbc7fbb3b6c |
| institution | OA Journals |
| issn | 2468-0540 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Non-coding RNA Research |
| spelling | doaj-art-6e9c9e6340c64188bda0fbbc7fbb3b6c2025-08-20T02:38:21ZengKeAi Communications Co., Ltd.Non-coding RNA Research2468-05402024-12-01941050106010.1016/j.ncrna.2024.06.002New mechanism of LncRNA: In addition to act as a ceRNAJiahao Zhang0Huike Zhu1Linjing Li2Yuting Gao3Boyi Yu4Guorong Ma5Xiaodong Jin6Yingbiao Sun7Department of Toxicology, School of Public Health, Lanzhou University, Lanzhou, 730000, China; Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, ChinaDepartment of Toxicology, School of Public Health, Lanzhou University, Lanzhou, 730000, ChinaInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing, 100049, ChinaInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; College of Life Sciences, Northwest Normal University, Gansu Province, Lanzhou, 730070, ChinaInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing, 100049, ChinaThe First Clinical Medical College of Gansu University of Chinese Medicine Gansu Provincial Hospital, Lanzhou, 730000, ChinaInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Corresponding author. Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China.Department of Toxicology, School of Public Health, Lanzhou University, Lanzhou, 730000, China; Corresponding author.Long non-coding RNAs (LncRNAs) are a class of RNA molecules with nucleic acid lengths ranging from 200 bp to 100 kb that cannot code for proteins, which are diverse and widely expressed in both animals and plants. Scholars have found that lncRNAs can regulate human physiological processes at the gene and protein levels, mainly through the regulation of epigenetic, transcriptional and post-transcriptional levels of genes and proteins, as well as in the immune response by regulating the expression of immune cells and inflammatory factors, and thus participate in the occurrence and development of a variety of diseases. From the downstream targets of lncRNAs, we summarize the new research progress of lncRNA mechanisms other than miRNA sponges in recent years, aiming to provide new ideas and directions for the study of lncRNA mechanisms.http://www.sciencedirect.com/science/article/pii/S246805402400101XLncRNAEpigeneticPost-translationalScaffolding proteinPeptide |
| spellingShingle | Jiahao Zhang Huike Zhu Linjing Li Yuting Gao Boyi Yu Guorong Ma Xiaodong Jin Yingbiao Sun New mechanism of LncRNA: In addition to act as a ceRNA Non-coding RNA Research LncRNA Epigenetic Post-translational Scaffolding protein Peptide |
| title | New mechanism of LncRNA: In addition to act as a ceRNA |
| title_full | New mechanism of LncRNA: In addition to act as a ceRNA |
| title_fullStr | New mechanism of LncRNA: In addition to act as a ceRNA |
| title_full_unstemmed | New mechanism of LncRNA: In addition to act as a ceRNA |
| title_short | New mechanism of LncRNA: In addition to act as a ceRNA |
| title_sort | new mechanism of lncrna in addition to act as a cerna |
| topic | LncRNA Epigenetic Post-translational Scaffolding protein Peptide |
| url | http://www.sciencedirect.com/science/article/pii/S246805402400101X |
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