Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures

Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cer...

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Main Authors: Ayşe Kartal, Ayşegül Neşe Çıtak Kurt, Tuğba Hirfanoğlu, Kürşad Aydın, Ayşe Serdaroğlu
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2015/783936
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author Ayşe Kartal
Ayşegül Neşe Çıtak Kurt
Tuğba Hirfanoğlu
Kürşad Aydın
Ayşe Serdaroğlu
author_facet Ayşe Kartal
Ayşegül Neşe Çıtak Kurt
Tuğba Hirfanoğlu
Kürşad Aydın
Ayşe Serdaroğlu
author_sort Ayşe Kartal
collection DOAJ
description Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a child with recurrent febrile seizures. The disease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis.
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institution Kabale University
issn 2090-6803
2090-6811
language English
publishDate 2015-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-6e99a84c041a4e4f8a6295524826626a2025-08-20T03:34:08ZengWileyCase Reports in Pediatrics2090-68032090-68112015-01-01201510.1155/2015/783936783936Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile SeizuresAyşe Kartal0Ayşegül Neşe Çıtak Kurt1Tuğba Hirfanoğlu2Kürşad Aydın3Ayşe Serdaroğlu4Department of Child Neurology, Inonu University Faculty of Medicine, Malatya, TurkeyDepartment of Child Neurology, Gazi University Faculty of Medicine, 06500 Ankara, TurkeyDepartment of Child Neurology, Gazi University Faculty of Medicine, 06500 Ankara, TurkeyDepartment of Child Neurology, Gazi University Faculty of Medicine, 06500 Ankara, TurkeyDepartment of Child Neurology, Gazi University Faculty of Medicine, 06500 Ankara, TurkeySubacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the onset. Herein, we report an unusual case of subacute sclerosing panencephalitis in a child with recurrent febrile seizures. The disease progressed with an appearance of myoclonic jerks, periodic high amplitude generalized complexes on EEG, and elevated titers of measles antibodies in cerebrospinal fluid leading to the final diagnosis of subacute sclerosing panencephalitis.http://dx.doi.org/10.1155/2015/783936
spellingShingle Ayşe Kartal
Ayşegül Neşe Çıtak Kurt
Tuğba Hirfanoğlu
Kürşad Aydın
Ayşe Serdaroğlu
Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
Case Reports in Pediatrics
title Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
title_full Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
title_fullStr Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
title_full_unstemmed Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
title_short Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures
title_sort subacute sclerosing panencephalitis in a child with recurrent febrile seizures
url http://dx.doi.org/10.1155/2015/783936
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