The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area
Increased levels of endotoxin found in rural and agricultural areas are an environmental exposure believed to cause a paradoxical proinflammatory effect on respiratory health that can exacerbate asthma. Previous studies involving adults have demonstrated an association between high endotoxin levels...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2011/290261 |
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| _version_ | 1832550423245881344 |
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| author | Joshua A Lawson James A Dosman Donna C Rennie Jeremy Beach Stephen C Newman Ambikaipakan Senthilselvan |
| author_facet | Joshua A Lawson James A Dosman Donna C Rennie Jeremy Beach Stephen C Newman Ambikaipakan Senthilselvan |
| author_sort | Joshua A Lawson |
| collection | DOAJ |
| description | Increased levels of endotoxin found in rural and agricultural areas are an environmental exposure believed to cause a paradoxical proinflammatory effect on respiratory health that can exacerbate asthma. Previous studies involving adults have demonstrated an association between high endotoxin levels and lower lung function. Apart from occupational settings, however, few studies have investigated the relationship between lung function and endotoxin exposure, such as environmental tobacco smoke, especially in children. This study examined the modifying effects of sex, pre-existing asthma and other environmental exposures, including tobacco smoke, in children living in rural communities in Saskatchewan. |
| format | Article |
| id | doaj-art-6e92dec41c894a74b1e41ce47a360dc5 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-6e92dec41c894a74b1e41ce47a360dc52025-02-03T06:06:50ZengWileyCanadian Respiratory Journal1198-22412011-01-01186e89e9410.1155/2011/290261The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural AreaJoshua A Lawson0James A Dosman1Donna C Rennie2Jeremy Beach3Stephen C Newman4Ambikaipakan Senthilselvan5Canadian Centre for Health and Safety in Agriculture, CanadaCanadian Centre for Health and Safety in Agriculture, CanadaCanadian Centre for Health and Safety in Agriculture, CanadaDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, CanadaDepartment of Public Health Sciences, School of Public Health Sciences, University of Alberta, Edmonton, Alberta, CanadaIncreased levels of endotoxin found in rural and agricultural areas are an environmental exposure believed to cause a paradoxical proinflammatory effect on respiratory health that can exacerbate asthma. Previous studies involving adults have demonstrated an association between high endotoxin levels and lower lung function. Apart from occupational settings, however, few studies have investigated the relationship between lung function and endotoxin exposure, such as environmental tobacco smoke, especially in children. This study examined the modifying effects of sex, pre-existing asthma and other environmental exposures, including tobacco smoke, in children living in rural communities in Saskatchewan.http://dx.doi.org/10.1155/2011/290261 |
| spellingShingle | Joshua A Lawson James A Dosman Donna C Rennie Jeremy Beach Stephen C Newman Ambikaipakan Senthilselvan The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area Canadian Respiratory Journal |
| title | The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area |
| title_full | The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area |
| title_fullStr | The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area |
| title_full_unstemmed | The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area |
| title_short | The Association between Endotoxin and Lung Function among Children and Adolescents Living in a Rural Area |
| title_sort | association between endotoxin and lung function among children and adolescents living in a rural area |
| url | http://dx.doi.org/10.1155/2011/290261 |
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